rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q5JSP0 | 725 | FGD3_HUMAN FYVE, RhoGEF and PH domain-contain... | 58 | 0.005 | 45.8 | 33 | 55 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 242 | Q5R5T1 | 737 | FGD3_PONAB FYVE, RhoGEF and PH domain-contain... | 58 | 0.006 | 45.8 | 33 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 243 | Q5BIM5 | 404 | ZFY27_BOVIN Protrudin OS=Bos taurus (Bovine).... | 88 | 0.006 | 45.1 | 30 | 45 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 244 | Q3TB82 | 279 | PKHF1_MOUSE Pleckstrin homology domain-contai... | 81 | 0.006 | 44.7 | 33 | 49 | GO:0005764; C:lysosome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:MGI. | 245 | Q80UZ0 | 1219 | FGD5_MOUSE FYVE, RhoGEF and PH domain-contain... | 54 | 0.007 | 45.4 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 246 | Q54IL5 | 1697 | UGT52_DICDI UDP-sugar-dependent glycosyltrans... | 57 | 0.009 | 45.1 | 33 | 49 | | | | | | | | | | | GO:0051507; F:beta-sitosterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0051505; F:cholesterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0051506; F:ergosterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051508; F:stigmasterol UDP-glucosyltransferase activity; IDA:dictyBase.::GO:0051509; F:tomatidine UDP-glucosyltransferase activity; IDA:dictyBase. | | | | | | | | | | GO:0030259; P:lipid glycosylation; IEA:InterPro.::GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 247 | Q96K21 | 471 | ZFY19_HUMAN Zinc finger FYVE domain-containin... | 56 | 0.009 | 44.7 | 36 | 55 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 248 | Q96S99 | 279 | PKHF1_HUMAN Pleckstrin homology domain-contai... | 83 | 0.015 | 43.5 | 34 | 51 | GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 249 | P39078 | 528 | TCPD_YEAST T-complex protein 1 subunit delta ... | 168 | 0.015 | 43.9 | 26 | 51 | GO:0005832; C:chaperonin-containing T-complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IDA:SGD. | | | | | | | | | | GO:0006457; P:protein folding; IDA:SGD. | 250 | Q91WB4 | 249 | PKHF2_MOUSE Pleckstrin homology domain-contai... | 72 | 0.018 | 42.7 | 36 | 47 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 251 | Q9H8W4 | 249 | PKHF2_HUMAN Pleckstrin homology domain-contai... | 72 | 0.019 | 42.7 | 36 | 47 | GO:0030133; C:transport vesicle; IDA:LIFEdb. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 252 | Q5RCD2 | 531 | TCPZ_PONAB T-complex protein 1 subunit zeta O... | 206 | 0.021 | 43.5 | 22 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 253 | Q8BUB4 | 400 | WDFY2_MOUSE WD repeat and FYVE domain-contain... | 71 | 0.037 | 42.7 | 28 | 54 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 254 | Q96P53 | 400 | WDFY2_HUMAN WD repeat and FYVE domain-contain... | 71 | 0.04 | 42.4 | 28 | 54 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 255 | P47208 | 540 | TCPD_CAEEL T-complex protein 1 subunit delta ... | 218 | 0.04 | 42.7 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; ISS:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040032; P:post-embryonic body morphogenesis; IMP:WormBase.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 256 | Q9NB32 | 533 | TCPD_AEDTR T-complex protein 1 subunit delta ... | 167 | 0.048 | 42.4 | 22 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 257 | Q9HN70 | 562 | THSA_HALSA Thermosome subunit alpha OS=(Halob... | 207 | 0.052 | 42.4 | 22 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 258 | O30560 | 557 | THS2_HALVD Thermosome subunit 2 OS=14742 / NC... | 140 | 0.06 | 42 | 26 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 259 | Q5R7K2 | 411 | ZFY27_PONAB Protrudin OS=Pongo abelii (Sumatr... | 88 | 0.061 | 42 | 31 | 43 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 260 | Q5T4F4 | 411 | ZFY27_HUMAN Protrudin OS=Homo sapiens (Human)... | 88 | 0.066 | 42 | 31 | 43 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; IDA:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 261 | Q9DAZ9 | 389 | ZFY19_MOUSE Zinc finger FYVE domain-containin... | 61 | 0.069 | 41.6 | 33 | 52 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 262 | Q7ZUV1 | 247 | PKHF2_DANRE Pleckstrin homology domain-contai... | 66 | 0.081 | 40.8 | 35 | 50 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 263 | P32609 | 515 | PEP7_YEAST Vacuolar segregation protein PEP7 ... | 85 | 0.087 | 41.6 | 28 | 38 | GO:0010009; C:external side of endosome membrane; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0000011; P:vacuole inheritance; IMP:SGD.::GO:0006904; P:vesicle docking involved in exocytosis; IMP:SGD.::GO:0006906; P:vesicle fusion; IMP:SGD. | 264 | Q6P7B7 | 404 | ZFY27_RAT Protrudin OS=Rattus norvegicus (Rat... | 126 | 0.11 | 41.2 | 30 | 41 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0031175; P:neuron projection development; IMP:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; IDA:UniProtKB. | 265 | Q5ZLY5 | 249 | PKHF2_CHICK Pleckstrin homology domain-contai... | 69 | 0.11 | 40.4 | 36 | 48 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 266 | Q5ZL36 | 406 | ZFY27_CHICK Protrudin OS=Gallus gallus (Chick... | 120 | 0.15 | 40.8 | 28 | 41 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. | 267 | P46550 | 539 | TCPZ_CAEEL T-complex protein 1 subunit zeta O... | 221 | 0.2 | 40.4 | 22 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006457; P:protein folding; IEA:InterPro. | 268 | P39079 | 546 | TCPZ_YEAST T-complex protein 1 subunit zeta O... | 223 | 0.23 | 40.4 | 22 | 44 | GO:0005832; C:chaperonin-containing T-complex; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IDA:SGD. | | | | | | | | | | GO:0006457; P:protein folding; IDA:SGD. | 269 | O94515 | 535 | TCPZ_SCHPO T-complex protein 1 subunit zeta O... | 219 | 0.27 | 40 | 21 | 42 | GO:0005832; C:chaperonin-containing T-complex; IDA:PomBase.::GO:0005856; C:cytoskeleton; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; ISS:PomBase. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:PomBase.::GO:0006457; P:protein folding; ISS:PomBase.::GO:0007021; P:tubulin complex assembly; IC:PomBase. | 270 | P98174 | 961 | FGD1_HUMAN FYVE, RhoGEF and PH domain-contain... | 58 | 0.29 | 40 | 31 | 47 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IDA:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0043088; P:regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 271 | Q3TXX3 | 415 | ZFY27_MOUSE Protrudin OS=Mus musculus (Mouse)... | 88 | 0.41 | 39.3 | 31 | 43 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0072659; P:protein localization in plasma membrane; ISS:UniProtKB. |