| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | P53191 | 635 | PIB2_YEAST Phosphatidylinositol 3-phosphate-b... | 38 | 0.000002 | 56.6 | 53 | 61 | GO:0005770; C:late endosome; TAS:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 152 | Q80U44 | 1528 | ZFY16_MOUSE Zinc finger FYVE domain-containin... | 71 | 0.000002 | 57 | 32 | 51 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 153 | Q6CL17 | 603 | VPS27_KLULA Vacuolar protein sorting-associat... | 99 | 0.000002 | 56.6 | 31 | 44 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 154 | P50999 | 527 | TCPD_SCHPO T-complex protein 1 subunit delta ... | 241 | 0.000002 | 56.2 | 25 | 45 | GO:0005832; C:chaperonin-containing T-complex; IDA:PomBase.::GO:0005856; C:cytoskeleton; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; ISS:PomBase. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:PomBase.::GO:0006457; P:protein folding; ISS:PomBase.::GO:0007021; P:tubulin complex assembly; IC:PomBase. | 155 | Q06651 | 286 | PIB1_YEAST E3 ubiquitin-protein ligase PIB1 O... | 78 | 0.000002 | 55.5 | 32 | 45 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD. | | | | | | | | | | GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 156 | Q8BL66 | 1411 | EEA1_MOUSE Early endosome antigen 1 OS=Mus mu... | 115 | 0.000002 | 57 | 28 | 45 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0005969; C:serine-pyruvate aminotransferase complex; IDA:MGI. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; ISS:UniProtKB. | 157 | Q96M96 | 766 | FGD4_HUMAN FYVE, RhoGEF and PH domain-contain... | 79 | 0.000003 | 56.6 | 32 | 49 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 158 | O70161 | 661 | PI51C_MOUSE Phosphatidylinositol 4-phosphate ... | 185 | 0.000003 | 56.2 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0001931; C:uropod; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; IDA:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 159 | Q05B78 | 254 | ZFY21_BOVIN Zinc finger FYVE domain-containin... | 65 | 0.000003 | 54.3 | 35 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 160 | Q7Z6J4 | 655 | FGD2_HUMAN FYVE, RhoGEF and PH domain-contain... | 108 | 0.000004 | 55.8 | 33 | 45 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 161 | Q5I6B8 | 688 | PI51C_RAT Phosphatidylinositol 4-phosphate 5-... | 185 | 0.000004 | 55.8 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0001931; C:uropod; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 162 | O24734 | 559 | THSA_SULTO Thermosome subunit alpha OS=Sulfol... | 216 | 0.000004 | 55.5 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 163 | P53451 | 536 | TCPD_TAKRU T-complex protein 1 subunit delta ... | 216 | 0.000004 | 55.5 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 164 | O93624 | 544 | THS_METTL Thermosome subunit OS=Methanococcus... | 207 | 0.000005 | 55.5 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 165 | P40343 | 622 | VPS27_YEAST Vacuolar protein sorting-associat... | 61 | 0.000005 | 55.5 | 38 | 49 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0045053; P:protein retention in Golgi apparatus; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD. | 166 | O60331 | 668 | PI51C_HUMAN Phosphatidylinositol 4-phosphate ... | 176 | 0.000005 | 55.5 | 30 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.::GO:0001931; C:uropod; TAS:UniProtKB. | | | | | | | | | | GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0034333; P:adherens junction assembly; TAS:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016337; P:cell-cell adhesion; TAS:UniProtKB.::GO:0072583; P:clathrin-mediated endocytosis; TAS:UniProtKB.::GO:0030593; P:neutrophil chemotaxis; TAS:UniProtKB.::GO:0006909; P:phagocytosis; TAS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; TAS:UniProtKB.::GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB. | 167 | Q6BSD6 | 732 | VPS27_DEBHA Vacuolar protein sorting-associat... | 63 | 0.000005 | 55.5 | 35 | 51 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 168 | P80313 | 544 | TCPH_MOUSE T-complex protein 1 subunit eta OS... | 249 | 0.000006 | 55.1 | 26 | 39 | GO:0005832; C:chaperonin-containing T-complex; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:MGI.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 169 | P48425 | 543 | THSB_THEAC Thermosome subunit beta OS=NBRC 15... | 189 | 0.000007 | 55.1 | 25 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 170 | Q9Y7M3 | 293 | YNT3_SCHPO FYVE-type zinc finger-containing p... | 116 | 0.000008 | 53.9 | 32 | 47 | GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 171 | Q13615 | 1198 | MTMR3_HUMAN Myotubularin-related protein 3 OS... | 122 | 0.000008 | 55.1 | 30 | 41 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; IDA:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB. | 172 | A1DFP5 | 729 | VPS27_NEOFI Vacuolar protein sorting-associat... | 115 | 0.000009 | 54.7 | 29 | 43 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 173 | Q15075 | 1411 | EEA1_HUMAN Early endosome antigen 1 OS=Homo s... | 125 | 0.000009 | 55.1 | 26 | 43 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; NAS:UniProtKB.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:UniProtKB. | | | | | | | | | | GO:0045022; P:early endosome to late endosome transport; NAS:UniProtKB.::GO:0016189; P:synaptic vesicle to endosome fusion; TAS:UniProtKB.::GO:0006906; P:vesicle fusion; IMP:UniProtKB. | 174 | O95405 | 1425 | ZFYV9_HUMAN Zinc finger FYVE domain-containin... | 59 | 0.00001 | 54.7 | 37 | 54 | GO:0031901; C:early endosome membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008236; F:serine-type peptidase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:UniProtKB.::GO:0007184; P:SMAD protein import into nucleus; IMP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB. | 175 | Q5PQT2 | 1194 | MTMR3_RAT Myotubularin-related protein 3 OS=R... | 63 | 0.00001 | 54.7 | 40 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB. | 176 | Q8K296 | 1196 | MTMR3_MOUSE Myotubularin-related protein 3 OS... | 63 | 0.00001 | 54.7 | 40 | 46 | | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004438; F:phosphatidylinositol-3-phosphatase activity; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:UniProtKB. | 177 | O04450 | 535 | TCPE_ARATH T-complex protein 1 subunit epsilo... | 211 | 0.00001 | 54.3 | 24 | 45 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 178 | P70182 | 546 | PI51A_MOUSE Phosphatidylinositol 4-phosphate ... | 180 | 0.00001 | 54.3 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:MGI. | | | | | | | | | | GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0010761; P:fibroblast migration; IMP:MGI.::GO:0048041; P:focal adhesion assembly; ISS:UniProtKB.::GO:0072661; P:protein targeting to plasma membrane; ISS:UniProtKB.::GO:0097178; P:ruffle assembly; ISS:UniProtKB. | 179 | Q9V2T5 | 558 | THSA_SULAC Thermosome subunit alpha OS=NBRC 1... | 216 | 0.00001 | 54.3 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 180 | Q4R6V2 | 541 | TCPE_MACFA T-complex protein 1 subunit epsilo... | 222 | 0.00001 | 53.9 | 24 | 44 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro. | 181 | P48643 | 541 | TCPE_HUMAN T-complex protein 1 subunit epsilo... | 222 | 0.00001 | 53.9 | 24 | 44 | GO:0005813; C:centrosome; IDA:MGI.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0051084; P:'de novo' posttranslational protein folding; TAS:Reactome.::GO:0009615; P:response to virus; IEP:UniProtKB. |
