| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53974 | 638 | ARK1_YEAST Actin-regulating kinase 1 OS=Sacch... | 300 | 5e-90 | 310 | 49 | 67 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0007015; P:actin filament organization; IMP:SGD.::GO:0000910; P:cytokinesis; TAS:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD. | 2 | Q9USS2 | 872 | PPK29_SCHPO Serine/threonine-protein kinase p... | 301 | 1e-88 | 312 | 49 | 68 | GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0065007; P:biological regulation; NAS:PomBase. | 3 | O43066 | 953 | PPK30_SCHPO Serine/threonine-protein kinase p... | 296 | 5e-86 | 306 | 48 | 67 | GO:0030479; C:actin cortical patch; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 4 | P40494 | 810 | PRK1_YEAST Actin-regulating kinase PRK1 OS=Sa... | 295 | 3e-85 | 300 | 46 | 67 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0007015; P:actin filament organization; IMP:SGD.::GO:0000910; P:cytokinesis; TAS:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD. | 5 | Q9UU85 | 650 | PPK38_SCHPO Protein kinase domain-containing ... | 293 | 3e-83 | 290 | 47 | 65 | GO:0030479; C:actin cortical patch; ISS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; ISS:PomBase.::GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 6 | P38080 | 1108 | AKL1_YEAST Serine/threonine-protein kinase AK... | 305 | 1e-69 | 258 | 42 | 62 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD. | 7 | Q3UHJ0 | 959 | AAK1_MOUSE AP2-associated protein kinase 1 OS... | 396 | 6e-69 | 254 | 38 | 55 | GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; ISS:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB. | | | | | | | | | | GO:0035612; F:AP-2 adaptor complex binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB. | 8 | F1SPM8 | 968 | AAK1_PIG AP2-associated protein kinase 1 OS=S... | 385 | 7e-69 | 254 | 38 | 57 | GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB. | | | | | | | | | | GO:0035612; F:AP-2 adaptor complex binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB. | 9 | F1MH24 | 957 | AAK1_BOVIN AP2-associated protein kinase 1 OS... | 385 | 2e-68 | 253 | 38 | 56 | GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; ISS:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB. | | | | | | | | | | GO:0035612; F:AP-2 adaptor complex binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB. | 10 | Q2M2I8 | 961 | AAK1_HUMAN AP2-associated protein kinase 1 OS... | 385 | 2e-68 | 253 | 38 | 56 | GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0030136; C:clathrin-coated vesicle; ISS:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; ISS:UniProtKB. | | | | | | | | | | GO:0035612; F:AP-2 adaptor complex binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0032880; P:regulation of protein localization; IDA:UniProtKB. | 11 | P0C1X8 | 962 | AAK1_RAT AP2-associated protein kinase 1 OS=R... | 386 | 1e-67 | 251 | 37 | 55 | GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0071439; C:clathrin complex; IDA:UniProtKB.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; IDA:UniProtKB. | | | | | | | | | | GO:0035612; F:AP-2 adaptor complex binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045747; P:positive regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:2000369; P:regulation of clathrin-mediated endocytosis; IDA:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB. | 12 | Q54VV7 | 1126 | Y0111_DICDI Probable serine/threonine-protein... | 295 | 7e-67 | 250 | 42 | 62 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q91Z96 | 1138 | BMP2K_MOUSE BMP-2-inducible protein kinase OS... | 330 | 1e-66 | 249 | 39 | 57 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019208; F:phosphatase regulator activity; IDA:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030500; P:regulation of bone mineralization; IDA:MGI. | 14 | Q9NSY1 | 1161 | BMP2K_HUMAN BMP-2-inducible protein kinase OS... | 290 | 2e-65 | 246 | 41 | 59 | GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q86HW6 | 798 | Y6461_DICDI Probable serine/threonine-protein... | 293 | 3e-62 | 233 | 42 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | O14976 | 1311 | GAK_HUMAN Cyclin-G-associated kinase OS=Homo ... | 295 | 5e-51 | 201 | 37 | 55 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 17 | P97874 | 1305 | GAK_RAT Cyclin-G-associated kinase OS=Rattus ... | 296 | 6e-50 | 197 | 36 | 55 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IDA:RGD.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 18 | Q99KY4 | 1305 | GAK_MOUSE Cyclin-G-associated kinase OS=Mus m... | 296 | 6e-50 | 197 | 36 | 56 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 19 | P57760 | 305 | STK16_RAT Serine/threonine-protein kinase 16 ... | 294 | 7e-25 | 111 | 30 | 51 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:RGD. | | | | | | | | | | GO:0071560; P:cellular response to transforming growth factor beta stimulus; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD. | 20 | Q6P3R8 | 708 | NEK5_HUMAN Serine/threonine-protein kinase Ne... | 279 | 9e-25 | 115 | 31 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 21 | Q9R0A5 | 511 | NEK3_MOUSE Serine/threonine-protein kinase Ne... | 289 | 1e-24 | 113 | 29 | 48 | GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 22 | O75716 | 305 | STK16_HUMAN Serine/threonine-protein kinase 1... | 295 | 1e-24 | 110 | 29 | 50 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 23 | P59241 | 397 | AURKA_RAT Aurora kinase A OS=Rattus norvegicu... | 274 | 7e-24 | 109 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0032355; P:response to estradiol stimulus; IEP:RGD. | 24 | P51954 | 1203 | NEK1_MOUSE Serine/threonine-protein kinase Ne... | 281 | 8e-24 | 112 | 29 | 50 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI. | 25 | Q7TSC3 | 627 | NEK5_MOUSE Serine/threonine-protein kinase Ne... | 271 | 3e-23 | 110 | 32 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q96PY6 | 1258 | NEK1_HUMAN Serine/threonine-protein kinase Ne... | 345 | 3e-23 | 111 | 28 | 48 | GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0000242; C:pericentriolar material; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 27 | O88697 | 305 | STK16_MOUSE Serine/threonine-protein kinase 1... | 294 | 4e-23 | 106 | 30 | 51 | GO:0005798; C:Golgi-associated vesicle; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 28 | P97477 | 395 | AURKA_MOUSE Aurora kinase A OS=Mus musculus (... | 278 | 5e-23 | 107 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 29 | Q54RJ4 | 979 | IKSA_DICDI Probable serine/threonine-protein ... | 310 | 5e-23 | 110 | 29 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | Q2TA06 | 402 | AURKA_BOVIN Aurora kinase A OS=Bos taurus (Bo... | 276 | 7e-23 | 106 | 30 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 31 | Q9SN43 | 489 | CIPKC_ARATH CBL-interacting serine/threonine-... | 293 | 2e-22 | 106 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |
