| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q9NS56 | 1045 | TOPRS_HUMAN E3 ubiquitin-protein ligase Topor... | 48 | 2.5 | 34.3 | 27 | 44 | GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0044547; F:DNA topoisomerase binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0051457; P:maintenance of protein location in nucleus; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB. | 362 | Q80Z37 | 1033 | TOPRS_MOUSE E3 ubiquitin-protein ligase Topor... | 48 | 2.7 | 34.3 | 27 | 44 | GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IDA:MGI. | 363 | Q803I4 | 336 | RING2_DANRE E3 ubiquitin-protein ligase RING2... | 109 | 2.8 | 33.9 | 29 | 43 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 364 | Q08273 | 121 | RBX1_YEAST RING-box protein HRT1 OS=Saccharom... | 109 | 2.8 | 32.3 | 23 | 40 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD. | 365 | Q00940 | 295 | PEX10_PICAN Peroxisome biogenesis factor 10 O... | 24 | 3 | 33.5 | 46 | 58 | GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro. | 366 | Q9NW38 | 375 | FANCL_HUMAN E3 ubiquitin-protein ligase FANCL... | 62 | 3.1 | 33.5 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043240; C:Fanconi anaemia nuclear complex; IDA:UniProtKB. | | | | | | | | | | GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB. | 367 | Q6A009 | 1767 | LTN1_MOUSE E3 ubiquitin-protein ligase lister... | 26 | 3.1 | 33.9 | 50 | 58 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB. | 368 | Q7KRW1 | 809 | TRC8_DROME Protein TRC8 homolog OS=Drosophila... | 23 | 3.1 | 33.9 | 43 | 61 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045926; P:negative regulation of growth; IMP:UniProtKB.::GO:0007418; P:ventral midline development; IMP:UniProtKB. | 369 | Q96EP1 | 664 | CHFR_HUMAN E3 ubiquitin-protein ligase CHFR O... | 51 | 3.2 | 33.9 | 31 | 39 | GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; IMP:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB. | 370 | Q75EN0 | 443 | RAD18_ASHGO Postreplication repair E3 ubiquit... | 61 | 3.4 | 33.5 | 30 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 371 | Q9UPN3 | 7388 | MACF1_HUMAN Microtubule-actin cross-linking f... | 79 | 3.4 | 33.9 | 28 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; NAS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; NAS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB. | 372 | Q9FIY7 | 1277 | SM3L3_ARATH Putative SWI/SNF-related matrix-a... | 87 | 3.5 | 33.9 | 29 | 46 | GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 373 | Q810L3 | 664 | CHFR_MOUSE E3 ubiquitin-protein ligase CHFR O... | 51 | 3.6 | 33.5 | 31 | 39 | GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI. | 374 | A0JM49 | 1696 | LTN1_XENTR E3 ubiquitin-protein ligase lister... | 26 | 3.6 | 33.9 | 50 | 58 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 375 | O35730 | 406 | RING1_MOUSE E3 ubiquitin-protein ligase RING1... | 92 | 4 | 33.5 | 27 | 40 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0001739; C:sex chromatin; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0048593; P:camera-type eye morphogenesis; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 376 | Q6FPI4 | 411 | RAD18_CANGA Postreplication repair E3 ubiquit... | 51 | 4.1 | 33.1 | 35 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 377 | Q6MGB6 | 406 | RING1_RAT E3 ubiquitin-protein ligase RING1 O... | 92 | 4.1 | 33.1 | 27 | 40 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 378 | Q9UT86 | 94 | APC11_SCHPO Anaphase-promoting complex subuni... | 36 | 4.2 | 31.2 | 42 | 56 | GO:0005680; C:anaphase-promoting complex; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IC:PomBase.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IC:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030071; P:regulation of mitotic metaphase/anaphase transition; IC:PomBase. | 379 | Q6IDS6 | 323 | C3H35_ARATH E3 ubiquitin-protein ligase makor... | 76 | 4.2 | 33.1 | 32 | 43 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 380 | Q66J69 | 344 | RNG2A_XENLA E3 ubiquitin-protein ligase RING2... | 92 | 4.4 | 33.1 | 27 | 40 | GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 381 | P34088 | 1042 | RAG1_RABIT V(D)J recombination-activating pro... | 30 | 4.4 | 33.5 | 47 | 63 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. | 382 | Q587N7 | 515 | TRIM5_CHLAE Tripartite motif-containing prote... | 82 | 4.5 | 33.1 | 32 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 383 | Q9VB08 | 435 | RING1_DROME E3 ubiquitin-protein ligase RING1... | 90 | 4.9 | 33.1 | 27 | 40 | GO:0008278; C:cohesin complex; IDA:UniProtKB.::GO:0035102; C:PRC1 complex; TAS:FlyBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IDA:UniProtKB.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0022008; P:neurogenesis; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0045498; P:sex comb development; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 384 | Q99PJ2 | 551 | TRIM8_MOUSE Probable E3 ubiquitin-protein lig... | 39 | 4.9 | 33.1 | 46 | 54 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 385 | Q7T308 | 474 | RN168_DANRE E3 ubiquitin-protein ligase RNF16... | 29 | 4.9 | 33.1 | 52 | 66 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 386 | Q9BZR9 | 551 | TRIM8_HUMAN Probable E3 ubiquitin-protein lig... | 39 | 5.1 | 33.1 | 46 | 54 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | | 387 | Q5D7J2 | 497 | TRIM5_PAPAN Tripartite motif-containing prote... | 82 | 5.1 | 33.1 | 32 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 388 | Q5UP58 | 841 | YR592_MIMIV Putative helicase R592 OS=Acantha... | 52 | 5.2 | 33.1 | 38 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 389 | Q5RF77 | 571 | CHFR_PONAB E3 ubiquitin-protein ligase CHFR O... | 51 | 5.4 | 33.1 | 31 | 39 | GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007093; P:mitotic cell cycle checkpoint; ISS:UniProtKB.::GO:0019941; P:modification-dependent protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 390 | Q5D7I3 | 495 | TRIM5_ERYPA Tripartite motif-containing prote... | 82 | 5.6 | 33.1 | 32 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 391 | Q867B5 | 1043 | RAG1_PIG V(D)J recombination-activating prote... | 30 | 5.7 | 33.1 | 47 | 60 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004519; F:endonuclease activity; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0033077; P:T cell differentiation in thymus; ISS:UniProtKB.::GO:0033151; P:V(D)J recombination; ISS:UniProtKB. |
