nucovid logo   NU COVID-19 Resource Collection

Variant analysis and visualization

TitleURLFeatures
Nextstrain SARS-CoV-2 resources https://nextstrain.org/ncov
  • Interactive phylogeographic visualization of SARS-CoV-2 genomic evolution and epidemic spread
  • Includes global as well as various regional-level analyses (by continents, countries, etc.)
  • Shows distribution of both nucleotide and amiono acid mutations across the viral genome
  • Data derived from GISAID
COG-UK: COV-GLUE http://cov-glue.cvr.gla.ac.uk/#/home
  • Powered by GISAID, provides a database for amino acid variations
  • Based on GLUE (Genes Linked by Underlying Evolution), a data-centric bioinformatics environment for virus sequence data
  • Allows users to submit their own sequneces (FASTA files) for phylogenetic placement and genome visualiation
COG-UK: Microreact https://microreact.org/project/COGconsortium
  • Continuous evaluation of the viral lineages circulating in the UK
  • Each unique viral sequence and its frequency can be traced through time and space using interactive map and phylogeny
SARS-CoV-2 Alignment Screen https://macman123.shinyapps.io/ugi-scov2-alignment-screen/
  • Visualization tool providing the distribution of SNPs and homoplasies across the genome
  • Tree can be pruned by sampling locations
  • Data derived from GISAID; latest update, 04/06/2020
  • Published in: https://doi.org/10.1016/j.meegid.2020.104351
COVID-19 Viral Genome Analysis Pipeline https://cov.lanl.gov/content/index
  • A collection of tools for analyzing and visualizing mutations of interest in the spike (e.g., Spike 614) and other proteins
  • Includes geographic and phylogenetic distribution, variant accumilatoion over time, sequence locator, etc.
  • Data drawn from GISAID
  • Published in: https://doi.org/10.1016/j.cell.2020.06.043
CNCB/NGDC Genome Variations https://ngdc.cncb.ac.cn/ncov/variation
  • Visualizes the distribution and statistics calculated from SARS-CoV-2 strains compared against a reference genome
  • Contains also spatiotemporal dynamics, phylogeny, and haplotype network analyses
  • Part of CNCB/NGDC Resource for Coronavirus 2019 (RCoV19)