Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPR024W
Length:
747
Number of sequences:
5887
Description:
YPR024W YME1 SGDID:S000006228, Chr XVI from 610481-612724, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331P46462    806   TERA_RAT Transitional endoplasmic reticulum A...2437e-42     167     37     58GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0016887; F:ATPase activity; IDA:RGD.::GO:0042802; F:identical protein binding; IDA:BHF-UCL.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005102; F:receptor binding; IDA:RGD.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:RGD.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:RGD.::GO:0051260; P:protein homooligomerization; IDA:RGD.
332Q01853    806   TERA_MOUSE Transitional endoplasmic reticulum...2437e-42     167     37     58GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005792; C:microsome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:MGI.::GO:0070842; P:aggresome assembly; IGI:MGI.::GO:0030970; P:retrograde protein transport, ER to cytosol; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:MGI.
333P55072    806   TERA_HUMAN Transitional endoplasmic reticulum...2437e-42     167     37     58GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000502; C:proteasome complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0031593; F:polyubiquitin binding; IDA:BHF-UCL.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; TAS:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; TAS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; NAS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0030970; P:retrograde protein transport, ER to cytosol; IDA:UniProtKB.
334P23787    805   TERA_XENLA Transitional endoplasmic reticulum...2478e-42     167     36     58GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:UniProtKB.
GO:0034214; P:protein hexamerization; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
335P34123    403   PRS6B_DICDI 26S protease regulatory subunit 6...2378e-42     161     39     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005838; C:proteasome regulatory particle; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004175; F:endopeptidase activity; ISS:dictyBase.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0030163; P:protein catabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; ISS:dictyBase.
336P78578    423   PRS6B_ASPNG 26S protease regulatory subunit 6...2411e-41     161     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
337O42587    405   PR6AA_XENLA 26S protease regulatory subunit 6...2351e-41     160     40     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
338P03974    806   TERA_PIG Transitional endoplasmic reticulum A...2432e-41     166     37     58GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006810; P:transport; IEA:UniProtKB-KW.
339P36612    448   PRS4_SCHPO 26S protease regulatory subunit 4 ...2451e-40     159     38     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IGI:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
340P33298    428   PRS6B_YEAST 26S protease regulatory subunit 6...2592e-40     158     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0045899; P:positive regulation of RNA polymerase II transcriptional preinitiation complex assembly; IMP:SGD.::GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
341P46468    1229   CDAT_PLAF7 Putative cell division cycle ATPas...2533e-40     163     33     60
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:GeneDB_Pfalciparum.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051726; P:regulation of cell cycle; ISS:GeneDB_Pfalciparum.
342Q8SQI9    387   PRS6B_ENCCU 26S protease regulatory subunit 6...2494e-40     156     35     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
343P46507    415   PRS6B_MANSE 26S protease regulatory subunit 6...2559e-40     155     37     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
344Q3UMC0    893   SPAT5_MOUSE Spermatogenesis-associated protei...2632e-39     160     35     55GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
345Q9DBY8    855   NVL_MOUSE Nuclear valosin-containing protein-...2812e-39     160     36     55GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
346Q9MUP8    890   YCF2_MESVI Protein ycf2 OS=Mesostigma viride....5054e-39     159     27     46GO:0009570; C:chloroplast stroma; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
347Q6CPV1    1000   PEX6_KLULA Peroxisomal biogenesis factor 6 OS...2454e-39     159     40     58
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0007031; P:peroxisome organization; IEA:UniProtKB-KW.
348Q63570    418   PRS6B_RAT 26S protease regulatory subunit 6B ...2564e-39     154     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:RGD.
GO:0030163; P:protein catabolic process; IEA:InterPro.
349P54775    418   PRS6B_MOUSE 26S protease regulatory subunit 6...2564e-39     154     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0001824; P:blastocyst development; IMP:MGI.::GO:0030163; P:protein catabolic process; IEA:InterPro.
350Q4R7L3    418   PRS6B_MACFA 26S protease regulatory subunit 6...2565e-39     154     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
351P43686    418   PRS6B_HUMAN 26S protease regulatory subunit 6...2565e-39     154     36     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
352Q3T030    418   PRS6B_BOVIN 26S protease regulatory subunit 6...2565e-39     154     36     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030163; P:protein catabolic process; IEA:InterPro.
353Q8MNV0    512   SPAST_CAEEL Probable spastin homolog spas-1 O...2275e-39     155     41     59GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0008017; F:microtubule binding; IDA:WormBase.::GO:0008568; F:microtubule-severing ATPase activity; NAS:UniProtKB.
GO:0001578; P:microtubule bundle formation; NAS:UniProtKB.::GO:0007019; P:microtubule depolymerization; IDA:WormBase.::GO:0051013; P:microtubule severing; IDA:UniProtKB.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0031117; P:positive regulation of microtubule depolymerization; IDA:UniProtKB.::GO:0034214; P:protein hexamerization; IDA:UniProtKB.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0040025; P:vulval development; IMP:WormBase.
354O15381    856   NVL_HUMAN Nuclear valosin-containing protein-...2747e-39     158     35     55GO:0016235; C:aggresome; IDA:HPA.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
355P40340    1379   TBP7_YEAST Tat-binding homolog 7 OS=Saccharom...2768e-39     159     36     55GO:0042406; C:extrinsic to endoplasmic reticulum membrane; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:SGD.::GO:0042393; F:histone binding; IDA:SGD.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0031936; P:negative regulation of chromatin silencing; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.
356Q5U3S1    488   KATL1_DANRE Katanin p60 ATPase-containing sub...2419e-39     154     38     59GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
357Q8NB90    893   SPAT5_HUMAN Spermatogenesis-associated protei...2712e-38     157     36     56GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
358O74894    389   PRS6B_SCHPO 26S protease regulatory subunit 6...2482e-38     151     38     55GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0016887; F:ATPase activity; ISS:PomBase.
GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:PomBase.
359O75449    491   KTNA1_HUMAN Katanin p60 ATPase-containing sub...2533e-38     152     36     56GO:0005813; C:centrosome; IDA:HPA.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051329; P:interphase of mitotic cell cycle; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
360A8XV40    542   SPAST_CAEBR Probable spastin homolog spas-1 O...2273e-38     153     41     59GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
GO:0034214; P:protein hexamerization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
361B5X3X5    486   KTNA1_SALSA Katanin p60 ATPase-containing sub...2535e-38     152     36     57GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008568; F:microtubule-severing ATPase activity; IEA:EC.
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