Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YPL031C
Length:
305
Number of sequences:
5887
Description:
YPL031C PHO85 SGDID:S000005952, Chr XVI from 492918-492018,493037-493021, Genome Release 64-1-1, reverse complement, Verified ORF, "Cyclin-dependent kinase, with ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901Q8VHF0    797   MARK3_RAT MAP/microtubule affinity-regulating...2162e-23     104     31     54GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
902Q5RCC4    478   KCC2A_PONAB Calcium/calmodulin-dependent prot...3062e-23     103     27     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
903Q9UQM7    478   KCC2A_HUMAN Calcium/calmodulin-dependent prot...3062e-23     103     27     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
904Q5ZJK4    486   STK4_CHICK Serine/threonine-protein kinase 4 ...2942e-23     103     28     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
905O88866    714   HUNK_MOUSE Hormonally up-regulated neu tumor-...2992e-23     104     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
906Q556S2    513   PAKH_DICDI Serine/threonine-protein kinase pa...2212e-23     103     29     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
907A0JLX3    433   SMK4A_MOUSE Sperm motility kinase 4A OS=Mus m...2982e-23     102     28     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
908P08413    542   KCC2B_RAT Calcium/calmodulin-dependent protei...3012e-23     103     29     47GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060291; P:long-term synaptic potentiation; IMP:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
909P11275    478   KCC2A_RAT Calcium/calmodulin-dependent protei...3062e-23     102     27     44GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0032839; C:dendrite cytoplasm; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0035235; P:ionotropic glutamate receptor signaling pathway; IDA:UniProtKB.
910P11798    478   KCC2A_MOUSE Calcium/calmodulin-dependent prot...3062e-23     102     27     44GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:MGI.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:MGI.
911P28652    542   KCC2B_MOUSE Calcium/calmodulin-dependent prot...3012e-23     103     29     47GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:MGI.
GO:0060466; P:activation of meiosis involved in egg activation; IMP:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0031558; P:induction of apoptosis in response to chemical stimulus; IDA:MGI.::GO:0002030; P:inhibitory G-protein coupled receptor phosphorylation; IDA:MGI.::GO:0050885; P:neuromuscular process controlling balance; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:MGI.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.::GO:0032222; P:regulation of synaptic transmission, cholinergic; IMP:MGI.::GO:0046686; P:response to cadmium ion; IDA:MGI.
912Q6DGS3    554   KC2D2_DANRE Calcium/calmodulin-dependent prot...3073e-23     103     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
913Q8R9T6    625   PKN1_THETN Probable serine/threonine-protein ...2763e-23     103     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
914Q05512    776   MARK2_MOUSE Serine/threonine-protein kinase M...2143e-23     104     32     52GO:0045180; C:basal cortex; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
915Q92918    833   M4K1_HUMAN Mitogen-activated protein kinase k...2223e-23     104     33     52
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008349; F:MAP kinase kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.
916Q9Z2W1    426   STK25_MOUSE Serine/threonine-protein kinase 2...3033e-23     102     27     45GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0051645; P:Golgi localization; IMP:MGI.::GO:0050772; P:positive regulation of axonogenesis; IMP:MGI.
917Q16W24    769   PLK4_AEDAE Serine/threonine-protein kinase PL...2953e-23     104     28     45GO:0005814; C:centriole; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
918P25390    1331   SSK22_YEAST Serine/threonine-protein kinase S...3203e-23     104     25     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.
919Q6C3J2    371   IPL1_YARLI Spindle assembly checkpoint kinase...2973e-23     101     27     45GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
920Q39030    471   KPK2_ARATH Serine/threonine-protein kinase At...3033e-23     102     28     47GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0045727; P:positive regulation of translation; TAS:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.
921Q9U1Y5    476   CHK2_CAEEL Serine/threonine-protein kinase ch...2293e-23     102     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
922Q64702    925   PLK4_MOUSE Serine/threonine-protein kinase PL...2954e-23     104     27     45GO:0005814; C:centriole; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; IMP:UniProtKB.
923Q54L81    462   Y0700_DICDI Probable serine/threonine-protein...3244e-23     102     28     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
924P87050    775   CDR2_SCHPO Mitosis inducer protein kinase cdr...2114e-23     103     32     52GO:0071341; C:medial cortical node; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IGI:PomBase.::GO:0071574; P:protein localization to medial cortex; IMP:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0008361; P:regulation of cell size; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
925Q9JLM8    756   DCLK1_MOUSE Serine/threonine-protein kinase D...3024e-23     103     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0048675; P:axon extension; IGI:MGI.::GO:0021952; P:central nervous system projection neuron axonogenesis; IGI:MGI.::GO:0048813; P:dendrite morphogenesis; IGI:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0001764; P:neuron migration; IGI:MGI.
926Q13554    666   KCC2B_HUMAN Calcium/calmodulin-dependent prot...3074e-23     103     29     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090129; P:positive regulation of synapse maturation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051924; P:regulation of calcium ion transport; TAS:UniProtKB.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:UniProtKB.::GO:0014733; P:regulation of skeletal muscle adaptation; TAS:UniProtKB.::GO:0051823; P:regulation of synapse structural plasticity; TAS:UniProtKB.
927Q8BZN4    639   NUAK2_MOUSE NUAK family SNF1-like kinase 2 OS...2294e-23     103     31     52
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.
928Q9C562    479   CIPKA_ARATH CBL-interacting serine/threonine-...2214e-23     102     33     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
929O08679    722   MARK2_RAT Serine/threonine-protein kinase MAR...2144e-23     103     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.
GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0001764; P:neuron migration; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
930Q7KZI7    788   MARK2_HUMAN Serine/threonine-protein kinase M...2144e-23     103     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; ISS:UniProtKB.
GO:0030010; P:establishment of cell polarity; IDA:UniProtKB.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IMP:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; IEP:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
931Q9LZW4    442   CIPKE_ARATH CBL-interacting serine/threonine-...2954e-23     102     30     46GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
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