Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YOL113W
Length:
655
Number of sequences:
5887
Description:
YOL113W SKM1 SGDID:S000005473, Chr XV from 104326-106293, Genome Release 64-1-1, Verified ORF, "Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; involved in down-regulation of sterol uptake; proposed to be a downstream effector of Cdc42p during polarized growth"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
871O42781    351   MAPK2_PNECA Mitogen-activated protein kinase ...2534e-19     92.8     28     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0000751; P:cell cycle arrest in response to pheromone; NAS:UniProtKB.
872P32577    450   CSK_RAT Tyrosine-protein kinase CSK OS=Rattus...2364e-19     94     28     46GO:0045121; C:membrane raft; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0070064; F:proline-rich region binding; IPI:BHF-UCL.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.
GO:0034332; P:adherens junction organization; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IDA:RGD.::GO:0045779; P:negative regulation of bone resorption; IDA:RGD.::GO:0008285; P:negative regulation of cell proliferation; IDA:RGD.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:RGD.::GO:0032715; P:negative regulation of interleukin-6 production; IDA:RGD.::GO:0033673; P:negative regulation of kinase activity; IDA:RGD.::GO:0010989; P:negative regulation of low-density lipoprotein particle clearance; IDA:RGD.::GO:0050765; P:negative regulation of phagocytosis; IDA:RGD.::GO:0048709; P:oligodendrocyte differentiation; IEP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0060368; P:regulation of Fc receptor mediated stimulatory signaling pathway; IDA:RGD.
873P83098    346   STLK_DROME Putative serine/threonine-protein ...2754e-19     92.8     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
874Q8N5S9    505   KKCC1_HUMAN Calcium/calmodulin-dependent prot...2284e-19     94.7     27     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0007268; P:synaptic transmission; TAS:Reactome.
875Q38868    541   CDPK9_ARATH Calcium-dependent protein kinase ...2344e-19     94.7     30     52GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; TAS:TAIR.
876A1D2C9    366   HOG1_NEOFI Mitogen-activated protein kinase h...2114e-19     92.8     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
877P27361    379   MK03_HUMAN Mitogen-activated protein kinase 3...2644e-19     93.2     28     48GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004707; F:MAP kinase activity; NAS:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071260; P:cellular response to mechanical stimulus; IEP:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035066; P:positive regulation of histone acetylation; IMP:BHF-UCL.::GO:0033129; P:positive regulation of histone phosphorylation; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
878Q8K045    878   PKN3_MOUSE Serine/threonine-protein kinase N3...1774e-19     95.5     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0007165; P:signal transduction; IEA:InterPro.
879Q8IU85    385   KCC1D_HUMAN Calcium/calmodulin-dependent prot...2365e-19     93.2     28     47GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0032793; P:positive regulation of CREB transcription factor activity; IDA:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0090023; P:positive regulation of neutrophil chemotaxis; ISS:UniProtKB.::GO:0050766; P:positive regulation of phagocytosis; IMP:UniProtKB.::GO:0060267; P:positive regulation of respiratory burst; IMP:UniProtKB.::GO:0050773; P:regulation of dendrite development; IMP:UniProtKB.::GO:0071622; P:regulation of granulocyte chemotaxis; IMP:UniProtKB.
880P53683    533   CDPK2_ORYSJ Calcium-dependent protein kinase ...2365e-19     94.7     30     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
881O75116    1388   ROCK2_HUMAN Rho-associated protein kinase 2 O...1845e-19     95.9     34     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005198; F:structural molecule activity; NAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051298; P:centrosome duplication; IMP:UniProtKB.::GO:0000910; P:cytokinesis; NAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; TAS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; TAS:UniProtKB.::GO:0045616; P:regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0051492; P:regulation of stress fiber assembly; TAS:UniProtKB.::GO:0006939; P:smooth muscle contraction; TAS:UniProtKB.
882Q8TGA9    357   HOG1_BLUGR Mitogen-activated protein kinase H...2365e-19     92.8     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
883Q39192    362   SRK2D_ARATH Serine/threonine-protein kinase S...1945e-19     92.8     34     53GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IGI:TAIR.::GO:0010029; P:regulation of seed germination; IGI:TAIR.::GO:0009739; P:response to gibberellin stimulus; IGI:TAIR.::GO:0009651; P:response to salt stress; IDA:TAIR.
884Q4WSF6    366   HOG1_ASPFU Mitogen-activated protein kinase h...2115e-19     92.8     30     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
885Q8CE90    535   MP2K7_MOUSE Dual specificity mitogen-activate...2525e-19     94.4     29     47GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
886P21708    380   MK03_RAT Mitogen-activated protein kinase 3 O...2635e-19     92.8     29     48GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0019369; P:arachidonic acid metabolic process; IEP:RGD.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000189; P:MAPK import into nucleus; IDA:RGD.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IEP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:UniProtKB.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:RGD.
887Q9W739    302   CDK1_RANDY Cyclin-dependent kinase 1 OS=Rana ...2425e-19     92     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
888A7KAL2    960   ATG1_PENCW Serine/threonine-protein kinase AT...2845e-19     95.5     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
889Q00859    355   MAPK_FUSSO Mitogen-activated protein kinase O...2615e-19     92.4     28     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC.
890Q9SIQ7    582   CDPKO_ARATH Calcium-dependent protein kinase ...2426e-19     94.7     29     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
891P11362    822   FGFR1_HUMAN Fibroblast growth factor receptor...3676e-19     95.1     25     45GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.::GO:0008201; F:heparin binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0000165; P:MAPK cascade; TAS:ProtInc.::GO:0001764; P:neuron migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; TAS:UniProtKB.::GO:0010863; P:positive regulation of phospholipase C activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0048705; P:skeletal system morphogenesis; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
892Q63844    380   MK03_MOUSE Mitogen-activated protein kinase 3...2636e-19     92.8     29     48GO:0005901; C:caveola; TAS:UniProtKB.::GO:0005856; C:cytoskeleton; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0031143; C:pseudopodium; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:MGI.::GO:0001784; F:phosphotyrosine binding; IMP:MGI.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051216; P:cartilage development; IDA:MGI.::GO:0072584; P:caveolin-mediated endocytosis; TAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:2000657; P:negative regulation of apolipoprotein binding; IMP:BHF-UCL.::GO:0009887; P:organ morphogenesis; IDA:MGI.::GO:0051493; P:regulation of cytoskeleton organization; TAS:UniProtKB.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:MGI.::GO:0043330; P:response to exogenous dsRNA; IDA:MGI.::GO:0019233; P:sensory perception of pain; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IMP:UniProtKB.
893Q8BYR2    1129   LATS1_MOUSE Serine/threonine-protein kinase L...2006e-19     95.5     28     46GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0009755; P:hormone-mediated signaling pathway; IDA:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB.::GO:0000819; P:sister chromatid segregation; ISS:UniProtKB.
894Q8BHI9    436   NIM1_MOUSE Serine/threonine-protein kinase NI...2696e-19     93.6     26     46
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
895Q61846    643   MELK_MOUSE Maternal embryonic leucine zipper ...2826e-19     94.7     27     47GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
896P45894    589   AAPK1_CAEEL 5'-AMP-activated protein kinase c...2856e-19     94.7     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.
897Q19266    597   KPC3_CAEEL Protein kinase C-like 3 OS=Caenorh...2116e-19     94.7     28     48GO:0016324; C:apical plasma membrane; IDA:WormBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
898Q9XUJ7    722   DKF1_CAEEL Serine/threonine-protein kinase dk...3456e-19     94.7     26     45GO:0030424; C:axon; IDA:WormBase.::GO:0005938; C:cell cortex; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005624; C:membrane fraction; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005886; C:plasma membrane; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.
899P16092    822   FGFR1_MOUSE Fibroblast growth factor receptor...3676e-19     95.1     25     45GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IPI:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:MGI.::GO:0008201; F:heparin binding; ISS:UniProtKB.
GO:0001525; P:angiogenesis; IGI:MGI.::GO:0060117; P:auditory receptor cell development; IMP:MGI.::GO:0060445; P:branching involved in salivary gland morphogenesis; IMP:MGI.::GO:0048469; P:cell maturation; IMP:MGI.::GO:0002062; P:chondrocyte differentiation; IGI:MGI.::GO:0030326; P:embryonic limb morphogenesis; IMP:MGI.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IMP:MGI.::GO:0060484; P:lung-associated mesenchyme development; IGI:MGI.::GO:0048762; P:mesenchymal cell differentiation; IGI:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0042474; P:middle ear morphogenesis; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0001759; P:organ induction; IMP:MGI.::GO:0042473; P:outer ear morphogenesis; IMP:MGI.::GO:0048339; P:paraxial mesoderm development; IGI:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IGI:MGI.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0043406; P:positive regulation of MAP kinase activity; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IGI:MGI.::GO:0010863; P:positive regulation of phospholipase C activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0060665; P:regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling; IDA:MGI.::GO:0048378; P:regulation of lateral mesodermal cell fate specification; IGI:MGI.::GO:0007605; P:sensory perception of sound; IMP:MGI.::GO:0001657; P:ureteric bud development; IGI:MGI.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.::GO:0021847; P:ventricular zone neuroblast division; IMP:UniProtKB.
900Q54DF2    1060   MRKA_DICDI Probable serine/threonine-protein ...2866e-19     95.1     26     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
901Q3U1V8    1077   M3K9_MOUSE Mitogen-activated protein kinase k...2516e-19     95.1     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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