UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YNL098C

Length:

322

Number of sequences:

5887

Description:

YNL098C RAS2 SGDID:S000005042, Chr XIV from 440570-439602, Genome Release 64-1-1, reverse complement, Verified ORF, "GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
901	Q8IXI1	618	MIRO2_HUMAN Mitochondrial Rho GTPase 2 OS=Hom...	163	0.00004	48.9	26	50	GO:0005829; C:cytosol; TAS:Reactome.::GO:0031307; C:integral to mitochondrial outer membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0019725; P:cellular homeostasis; IMP:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
902	Q94263	625	MIRO_CAEEL Mitochondrial Rho GTPase OS=Caenor...	163	0.00004	48.5	26	49	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
903	Q54FK2	184	RABN2_DICDI Ras-related protein RabN2 OS=Dict...	174	0.00005	47	22	52
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
904	Q623S8	637	MIRO_CAEBR Mitochondrial Rho GTPase OS=Caenor...	171	0.00005	48.5	26	47	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
905	Q54EW9	194	RABU_DICDI Ras-related protein RabU OS=Dictyo...	183	0.00006	46.6	25	45
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
906	O94844	696	RHBT1_HUMAN Rho-related BTB domain-containing...	200	0.0001	47.4	26	46	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
907	Q298L5	649	MIRO_DROPS Mitochondrial Rho GTPase OS=Drosop...	133	2.7	33.5	23	44	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
908	Q5ZM83	618	MIRO2_CHICK Mitochondrial Rho GTPase 2 OS=Gal...	161	0.0002	47	25	50	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
909	Q5ZM73	619	MIRO1_CHICK Mitochondrial Rho GTPase 1 OS=Gal...	175	0.0002	46.6	25	45	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
910	Q8N4Z0	105	RAB42_HUMAN Putative Ras-related protein Rab-...	59	0.0002	43.5	41	63	GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
911	Q9BYZ6	727	RHBT2_HUMAN Rho-related BTB domain-containing...	200	0.0002	46.2	26	45	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
912	Q8IMX7	652	MIRO_DROME Mitochondrial Rho GTPase OS=Drosop...	186	0.0003	45.8	24	43	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IMP:FlyBase.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0048489; P:synaptic vesicle transport; IMP:FlyBase.
913	Q91V93	728	RHBT2_MOUSE Rho-related BTB domain-containing...	200	0.0003	45.8	26	45	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
914	Q6T311	187	ARL9_HUMAN ADP-ribosylation factor-like prote...	125	0.0006	43.5	26	47	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
915	P48559	417	YPT11_YEAST GTP-binding protein YPT11 OS=Sacc...	166	0.0008	44.3	28	43	GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0048309; P:endoplasmic reticulum inheritance; IMP:SGD.::GO:0048313; P:Golgi inheritance; IGI:SGD.::GO:0051645; P:Golgi localization; IMP:SGD.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
916	B5VQB6	417	YPT11_YEAS6 GTP-binding protein YPT11 OS=Sacc...	166	0.0008	44.3	28	43	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
917	A6ZSH6	417	YPT11_YEAS7 GTP-binding protein YPT11 OS=Sacc...	166	0.0008	44.3	28	43	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
918	Q7TSA0	622	MIRO2_RAT Mitochondrial Rho GTPase 2 OS=Rattu...	163	0.0009	44.7	25	49	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
919	B3LPD8	417	YPT11_YEAS1 GTP-binding protein YPT11 OS=Sacc...	104	0.001	44.3	29	47	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
920	Q8JZN7	620	MIRO2_MOUSE Mitochondrial Rho GTPase 2 OS=Mus...	163	0.001	43.9	25	49	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.::GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
921	Q02804	198	ARL3_YEAST ADP-ribosylation factor-like prote...	129	0.001	42.7	24	47	GO:0005794; C:Golgi apparatus; IDA:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:SGD.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.
									GO:0043001; P:Golgi to plasma membrane protein transport; IMP:SGD.::GO:0033365; P:protein localization to organelle; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
922	Q8N4G2	192	ARL14_HUMAN ADP-ribosylation factor-like prot...	119	0.001	42.7	25	50	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
923	P39722	662	GEM1_YEAST Mitochondrial Rho GTPase 1 OS=Sacc...	188	0.001	43.9	24	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
									GO:0005509; F:calcium ion binding; IDA:SGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.
									GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0010821; P:regulation of mitochondrion organization; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
924	Q54SD0	221	RABS_DICDI Ras-related protein RabS OS=Dictyo...	131	0.001	43.1	26	49	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
925	Q5S007	2527	LRRK2_HUMAN Leucine-rich repeat serine/threon...	134	0.001	44.3	24	47	GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL.
									GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL.
926	Q99PE9	201	ARL4D_MOUSE ADP-ribosylation factor-like prot...	121	0.002	42.4	24	43	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
927	Q4R4S4	186	ARL8B_MACFA ADP-ribosylation factor-like prot...	127	0.002	42	28	45	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
928	Q19143	199	KBRAS_CAEEL NF-kappa-B inhibitor-interacting ...	112	0.002	42.4	34	51	GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:InterPro.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
929	Q5E9M9	618	MIRO2_BOVIN Mitochondrial Rho GTPase 2 OS=Bos...	163	0.003	43.1	26	49	GO:0031307; C:integral to mitochondrial outer membrane; ISS:UniProtKB.
									GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0019725; P:cellular homeostasis; ISS:UniProtKB.::GO:0047497; P:mitochondrion transport along microtubule; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
930	Q1ZXB7	147	RABK2_DICDI Ras-related protein RabK2 OS=Dict...	102	0.003	40.8	27	52	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
931	Q66HA6	186	ARL8B_RAT ADP-ribosylation factor-like protei...	127	0.003	41.6	27	45	GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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