Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YMR015C
Length:
538
Number of sequences:
5887
Description:
YMR015C ERG5 SGDID:S000004617, Chr XIII from 302485-300869, Genome Release 64-1-1, reverse complement, Verified ORF, "C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q64464    503   CP3AD_MOUSE Cytochrome P450 3A13 OS=Mus muscu...2389e-17     86.7     28     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0010628; P:positive regulation of gene expression; IMP:MGI.
62Q59990    444   CP120_SYNY3 Putative cytochrome P450 120 OS=S...4299e-17     86.3     22     43
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
63Q9LJK2    468   ABAH4_ARATH Abscisic acid 8'-hydroxylase 4 OS...5031e-16     86.3     22     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0010295; F:(+)-abscisic acid 8'-hydroxylase activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
64Q9V773    501   C6A20_DROME Probable cytochrome P450 6a20 OS=...2151e-16     86.3     32     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
GO:0002118; P:aggressive behavior; IMP:FlyBase.
65P24463    503   CP3AC_CANFA Cytochrome P450 3A12 OS=Canis fam...2351e-16     86.3     28     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
66P51870    526   CP4F5_RAT Cytochrome P450 4F5 OS=Rattus norve...1861e-16     86.3     24     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006954; P:inflammatory response; TAS:RGD.::GO:0006691; P:leukotriene metabolic process; IMP:RGD.
67P51871    537   CP4F6_RAT Cytochrome P450 4F6 OS=Rattus norve...1861e-16     86.3     24     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0006954; P:inflammatory response; TAS:RGD.::GO:0006691; P:leukotriene metabolic process; IMP:RGD.
68Q8K4D6    507   CP4X1_RAT Cytochrome P450 4X1 OS=Rattus norve...1851e-16     86.3     26     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
69Q64417    503   CP3AE_CAVPO Cytochrome P450 3A14 OS=Cavia por...3891e-16     86.3     25     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
70Q9VXY0    495   CP4S3_DROME Probable cytochrome P450 4s3 OS=D...2112e-16     85.9     29     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
71Q27589    501   CP4D2_DROME Cytochrome P450 4d2 OS=Drosophila...1792e-16     85.9     28     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
72Q6V0L0    522   CP26C_HUMAN Cytochrome P450 26C1 OS=Homo sapi...4022e-16     85.9     22     40GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008401; F:retinoic acid 4-hydroxylase activity; IDA:BHF-UCL.::GO:0001972; F:retinoic acid binding; IDA:BHF-UCL.
GO:0009952; P:anterior/posterior pattern specification; ISS:BHF-UCL.::GO:0007417; P:central nervous system development; ISS:BHF-UCL.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; NAS:BHF-UCL.::GO:0014032; P:neural crest cell development; ISS:BHF-UCL.::GO:0048284; P:organelle fusion; ISS:BHF-UCL.::GO:0034653; P:retinoic acid catabolic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
73Q64409    503   CP3AH_CAVPO Cytochrome P450 3A17 OS=Cavia por...2062e-16     85.5     30     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
74Q02928    519   CP4AB_HUMAN Cytochrome P450 4A11 OS=Homo sapi...1822e-16     85.5     29     49GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; IDA:UniProtKB.
GO:0018685; F:alkane 1-monooxygenase activity; IDA:BHF-UCL.::GO:0008392; F:arachidonic acid epoxygenase activity; IDA:UniProtKB.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050051; F:leukotriene-B4 20-monooxygenase activity; IDA:UniProtKB.
GO:0019373; P:epoxygenase P450 pathway; IDA:UniProtKB.::GO:0032305; P:positive regulation of icosanoid secretion; IMP:UniProtKB.::GO:0003095; P:pressure natriuresis; IEP:UniProtKB.::GO:0003091; P:renal water homeostasis; IEP:UniProtKB.::GO:0055078; P:sodium ion homeostasis; IEP:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome.
75P24464    508   CP4AC_RAT Cytochrome P450 4A12 OS=Rattus norv...1822e-16     85.5     29     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.
76P82712    521   CCD1P_DROME Probable cytochrome P450 12d1 pro...1713e-16     85.5     33     50GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
77P14580    510   CP4A6_RABIT Cytochrome P450 4A6 OS=Oryctolagu...1823e-16     85.1     29     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
78O35728    507   CP4AE_MOUSE Cytochrome P450 4A14 OS=Mus muscu...3723e-16     85.1     24     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
79O93323    492   CP26A_XENLA Cytochrome P450 26A1 OS=Xenopus l...3833e-16     85.1     22     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
80Q54DT2    487   C516A_DICDI Probable cytochrome P450 516A1 OS...1933e-16     85.1     30     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
81Q9V4U7    509   C6A14_DROME Probable cytochrome P450 6a14 OS=...2123e-16     85.1     28     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
82P79401    503   CP3AT_PIG Cytochrome P450 3A29 OS=Sus scrofa ...1843e-16     85.1     29     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
83Q69F95    466   C85A_PHAVU Cytochrome P450 85A OS=Phaseolus v...4694e-16     84.7     23     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
84O44221    522   CP4E5_DROMT Cytochrome P450 4e5, mitochondria...1754e-16     84.7     29     46GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
85Q6EIG3    511   CP26B_DANRE Cytochrome P450 26B1 OS=Danio rer...3794e-16     84.7     24     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
GO:0060536; P:cartilage morphogenesis; IMP:ZFIN.::GO:0060365; P:coronal suture morphogenesis; IMP:ZFIN.::GO:0048701; P:embryonic cranial skeleton morphogenesis; IMP:ZFIN.::GO:0060323; P:head morphogenesis; IMP:ZFIN.::GO:0048387; P:negative regulation of retinoic acid receptor signaling pathway; IDA:UniProtKB.::GO:0030278; P:regulation of ossification; IMP:ZFIN.::GO:0034653; P:retinoic acid catabolic process; IMP:ZFIN.
86O23051    490   KAO1_ARATH Ent-kaurenoic acid oxidase 1 OS=Ar...4376e-16     84.3     23     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051777; F:ent-kaurenoate oxidase activity; IDA:TAIR.::GO:0020037; F:heme binding; IEA:InterPro.
GO:0009686; P:gibberellin biosynthetic process; TAS:TAIR.
87Q9V769    499   C6A22_DROME Cytochrome P450 6a22 OS=Drosophil...2106e-16     84.3     31     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
88P79102    507   CP3AS_BOVIN Cytochrome P450 3A28 OS=Bos tauru...1906e-16     84     29     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
89Q7KR10    521   CCD1D_DROME Probable cytochrome P450 12d1 dis...1718e-16     84     33     50GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0030342; F:1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity; ISS:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
90Q9V770    501   C6A17_DROME Probable cytochrome P450 6a17 OS=...2148e-16     83.6     27     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
GO:0040040; P:thermosensory behavior; IMP:FlyBase.
91P10611    510   CP4A4_RABIT Cytochrome P450 4A4 OS=Oryctolagu...1829e-16     83.6     29     49GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.
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