UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YBR103W

Length:

535

Number of sequences:

5887

Description:

YBR103W SIF2 SGDID:S000000307, Chr II from 447709-449316, Genome Release 64-1-1, Verified ORF, "WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q0P593	415	WDR69_BOVIN Outer row dynein assembly protein...	78	1.5	35	23	49	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
32	Q5BK30	415	WDR69_RAT Outer row dynein assembly protein 1...	254	0.00009	48.5	23	39	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
33	Q9DAJ4	315	WDR83_MOUSE WD repeat domain-containing prote...	245	0.000008	51.6	22	37	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
34	Q9UTN4	509	PFS2_SCHPO Polyadenylation factor subunit 2 O...	273	0.0000000001	67.4	23	41	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:PomBase.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0006378; P:mRNA polyadenylation; ISS:PomBase.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:PomBase.
35	Q6P2Y2	415	WDR69_XENTR Outer row dynein assembly protein...	251	0.0000002	57	24	39	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
36	Q8N136	415	WDR69_HUMAN Outer row dynein assembly protein...	251	0.00000007	58.5	24	38	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
37	Q54D08	304	LST8_DICDI Protein LST8 homolog OS=Dictyostel...	149	0.0002	47	26	42	GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
									GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
38	Q5XGI5	314	WDR83_XENTR WD repeat domain-containing prote...	104	0.032	40	27	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
39	Q93794	587	SEL10_CAEEL F-box/WD repeat-containing protei...	275	0.000003	53.5	20	42	GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB.
40	Q54PE0	922	PWP2_DICDI Periodic tryptophan protein 2 homo...	262	0.0000000009	65.1	25	45	GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005730; C:nucleolus; ISS:dictyBase.
									GO:0030515; F:snoRNA binding; ISS:dictyBase.
									GO:0006364; P:rRNA processing; ISS:dictyBase.
41	Q09406	534	A16L2_CAEEL Autophagic-related protein 16.2 O...	80	0.15	38.5	31	48
									GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.
42	Q5FWQ6	415	WDR69_XENLA Outer row dynein assembly protein...	252	0.0000003	56.2	25	40	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
43	P90587	601	WD66_PHYPO 66 kDa stress protein OS=Physarum ...	91	0.074	39.7	23	52
44	Q09990	665	LIN23_CAEEL F-box/WD repeat-containing protei...	187	0.00002	50.8	22	44	GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase.
									GO:0046983; F:protein dimerization activity; IEA:InterPro.
									GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.
45	Q8VEJ4	485	NLE1_MOUSE Notchless protein homolog 1 OS=Mus...	78	2.4	34.7	24	46	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0001826; P:inner cell mass cell differentiation; IMP:MGI.::GO:0007219; P:Notch signaling pathway; IDA:MGI.
46	Q1LV15	415	WDR69_DANRE Outer row dynein assembly protein...	65	0.65	36.2	31	52	GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
									GO:0070286; P:axonemal dynein complex assembly; IMP:UniProtKB.::GO:0060285; P:ciliary cell motility; IMP:UniProtKB.::GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:UniProtKB.
47	Q498M4	334	WDR5_RAT WD repeat-containing protein 5 OS=Ra...	145	0.001	44.7	24	42	GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
48	P61965	334	WDR5_MOUSE WD repeat-containing protein 5 OS=...	145	0.001	44.7	24	42	GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001501; P:skeletal system development; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49	P61964	334	WDR5_HUMAN WD repeat-containing protein 5 OS=...	145	0.001	44.7	24	42	GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; IDA:UniProtKB.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0051568; P:histone H3-K4 methylation; IDA:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; IDA:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; IDA:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50	Q93847	395	YZLL_CAEEL Uncharacterized WD repeat-containi...	167	0.029	40.4	20	47
51	Q2KIG2	334	WDR5_BOVIN WD repeat-containing protein 5 OS=...	145	0.001	44.7	24	42	GO:0000123; C:histone acetyltransferase complex; ISS:UniProtKB.::GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0048188; C:Set1C/COMPASS complex; ISS:UniProtKB.
									GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.
									GO:0051568; P:histone H3-K4 methylation; ISS:UniProtKB.::GO:0043984; P:histone H4-K16 acetylation; ISS:UniProtKB.::GO:0043981; P:histone H4-K5 acetylation; ISS:UniProtKB.::GO:0043982; P:histone H4-K8 acetylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52	O75083	606	WDR1_HUMAN WD repeat-containing protein 1 OS=...	104	0.021	41.2	29	46	GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.
									GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0007605; P:sensory perception of sound; TAS:ProtInc.
53	Q9W7F2	607	WDR1A_XENLA WD repeat-containing protein 1-A ...	101	3	34.3	24	47	GO:0005884; C:actin filament; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
									GO:0003779; F:actin binding; ISS:UniProtKB.
									GO:0030043; P:actin filament fragmentation; IDA:UniProtKB.
54	Q09715	614	TUP11_SCHPO Transcriptional repressor tup11 O...	263	0.000000005	62.4	22	43	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0042393; F:histone binding; IDA:PomBase.::GO:0003714; F:transcription corepressor activity; IGI:PomBase.
									GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006342; P:chromatin silencing; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55	C4YFX2	511	TUP1_CANAW Transcriptional repressor TUP1 OS=...	178	0.015	41.6	28	41
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56	P0CY34	512	TUP1_CANAL Transcriptional repressor TUP1 OS=...	178	0.015	41.6	28	41	GO:0005625; C:soluble fraction; IDA:CGD.
									GO:0016337; P:cell-cell adhesion; IMP:CGD.::GO:0071280; P:cellular response to copper ion; IMP:CGD.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0044409; P:entry into host; IMP:CGD.::GO:0051834; P:evasion or tolerance of defenses of other organism involved in symbiotic interaction; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0045827; P:negative regulation of isoprenoid metabolic process; IMP:CGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:CGD.::GO:0009405; P:pathogenesis; IMP:CGD.::GO:0009372; P:quorum sensing; IMP:CGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57	Q9C1X0	297	YN55_SCHPO Uncharacterized WD repeat-containi...	113	0.004	43.1	25	48	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase.
									GO:0045292; P:nuclear mRNA cis splicing, via spliceosome; ISS:PomBase.
58	Q9V3J8	361	WDS_DROME Protein will die slowly OS=Drosophi...	221	0.046	39.7	19	41	GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IPI:FlyBase.::GO:0005875; C:microtubule associated complex; IDA:FlyBase.::GO:0048188; C:Set1C/COMPASS complex; IDA:FlyBase.
									GO:0051568; P:histone H3-K4 methylation; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.
59	Q9FLX9	473	NLE1_ARATH Notchless protein homolog OS=Arabi...	65	0.83	36.2	28	52	GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
60	Q9C270	899	PWP2_NEUCR Periodic tryptophan protein 2 homo...	273	0.012	42.4	19	39
61	P54686	597	WD42_DICDI WD repeat-containing protein 2 hom...	68	7.6	33.1	28	50	GO:0060187; C:cell pole; IDA:dictyBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0001891; C:phagocytic cup; IDA:dictyBase.
									GO:0030042; P:actin filament depolymerization; IMP:dictyBase.::GO:0008283; P:cell proliferation; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0006907; P:pinocytosis; IMP:dictyBase.

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