rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O94142 | 525 | KO1_GIBFU Ent-kaurene oxidase OS=moniliforme)... | 530 | 4e-63 | 221 | 31 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0052617; F:ent-kaur-16-en-19-al oxidase activity; IEA:EC.::GO:0052616; F:ent-kaur-16-en-19-ol oxidase activity; IEA:EC.::GO:0052615; F:ent-kaurene oxidase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010241; P:ent-kaurene oxidation to kaurenoic acid; IEA:EC.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 2 | Q701P2 | 525 | KO1_GIBIN Ent-kaurene oxidase OS=proliferatum... | 494 | 4e-63 | 221 | 31 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0052617; F:ent-kaur-16-en-19-al oxidase activity; IEA:EC.::GO:0052616; F:ent-kaur-16-en-19-ol oxidase activity; IEA:EC.::GO:0052615; F:ent-kaurene oxidase activity; IEA:EC.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010241; P:ent-kaurene oxidation to kaurenoic acid; IEA:EC. | 3 | P48416 | 545 | CP10_LYMST Cytochrome P450 10 OS=Lymnaea stag... | 203 | 6e-17 | 87.4 | 29 | 48 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 4 | P10614 | 530 | CP51_YEAST Lanosterol 14-alpha demethylase OS... | 228 | 0.000000000000001 | 82.8 | 30 | 48 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008398; F:sterol 14-demethylase activity; IDA:SGD. | | | | | | | | | | GO:0006696; P:ergosterol biosynthetic process; IMP:SGD. | 5 | Q1ZXH9 | 466 | CP51_DICDI Probable lanosterol 14-alpha demet... | 387 | 0.000000000000005 | 80.9 | 25 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 6 | Q9LIP5 | 500 | C71BW_ARATH Cytochrome P450 71B35 OS=Arabidop... | 397 | 0.00000000000001 | 80.1 | 22 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 7 | P93846 | 492 | CP51_SORBI Obtusifoliol 14-alpha demethylase ... | 366 | 0.00000000000005 | 78.2 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 8 | Q9DBG1 | 533 | CP27A_MOUSE Sterol 26-hydroxylase, mitochondr... | 405 | 0.00000000000006 | 77.8 | 24 | 41 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 9 | Q07217 | 514 | CP11A_ONCMY Cholesterol side-chain cleavage e... | 203 | 0.0000000000001 | 77 | 26 | 44 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 10 | P17178 | 533 | CP27A_RAT Sterol 26-hydroxylase, mitochondria... | 283 | 0.0000000000001 | 76.6 | 25 | 42 | | | | | | | | | | | GO:0047749; F:cholestanetriol 26-monooxygenase activity; IEA:EC.::GO:0031073; F:cholesterol 26-hydroxylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:RGD. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IDA:RGD.::GO:0006706; P:steroid catabolic process; TAS:RGD. | 11 | Q9VE00 | 536 | C12A4_DROME Probable cytochrome P450 12a4, mi... | 217 | 0.0000000000001 | 76.6 | 28 | 48 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0017085; P:response to insecticide; IMP:FlyBase. | 12 | Q9UVC3 | 512 | CP51_CUNEL Lanosterol 14-alpha demethylase OS... | 358 | 0.0000000000001 | 76.6 | 23 | 43 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 13 | P14263 | 528 | CP51_CANTR Lanosterol 14-alpha demethylase OS... | 259 | 0.0000000000002 | 76.3 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 14 | P93596 | 453 | CP51_WHEAT Obtusifoliol 14-alpha demethylase ... | 372 | 0.0000000000002 | 75.9 | 24 | 40 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 15 | O14442 | 524 | CP51_UNCNE Eburicol 14-alpha-demethylase OS=U... | 265 | 0.0000000000003 | 75.9 | 28 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 16 | Q5IZM4 | 452 | CP51_MYCVP Lanosterol 14-alpha demethylase OS... | 274 | 0.0000000000003 | 75.1 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 17 | Q9SAA9 | 488 | CP511_ARATH Sterol 14-demethylase OS=Arabidop... | 329 | 0.0000000000005 | 75.1 | 25 | 43 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.::GO:0008398; F:sterol 14-demethylase activity; TAS:TAIR. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IMP:TAIR. | 18 | P08684 | 503 | CP3A4_HUMAN Cytochrome P450 3A4 OS=Homo sapie... | 262 | 0.0000000000005 | 74.7 | 25 | 43 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0047638; F:albendazole monooxygenase activity; IEA:EC.::GO:0034875; F:caffeine oxidase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.::GO:0019825; F:oxygen binding; TAS:ProtInc.::GO:0050591; F:quinine 3-monooxygenase activity; IEA:EC.::GO:0005496; F:steroid binding; IDA:BHF-UCL.::GO:0033780; F:taurochenodeoxycholate 6alpha-hydroxylase activity; IEA:EC.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:BHF-UCL.::GO:0070576; F:vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0030343; F:vitamin D3 25-hydroxylase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009822; P:alkaloid catabolic process; IDA:BHF-UCL.::GO:0008209; P:androgen metabolic process; TAS:BHF-UCL.::GO:0042738; P:exogenous drug catabolic process; IDA:BHF-UCL.::GO:0046483; P:heterocycle metabolic process; IDA:BHF-UCL.::GO:0016098; P:monoterpenoid metabolic process; IDA:BHF-UCL.::GO:0070989; P:oxidative demethylation; IDA:BHF-UCL.::GO:0006706; P:steroid catabolic process; IMP:BHF-UCL.::GO:0042359; P:vitamin D metabolic process; IC:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 19 | Q9LTM3 | 502 | C71BK_ARATH Cytochrome P450 71B20 OS=Arabidop... | 284 | 0.0000000000006 | 74.7 | 24 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 20 | P33268 | 503 | CP3A8_MACFA Cytochrome P450 3A8 OS=Macaca fas... | 262 | 0.0000000000006 | 74.3 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 21 | Q8SPK1 | 504 | CP4AO_PIG Cytochrome P450 4A24 OS=Sus scrofa ... | 191 | 0.0000000000006 | 74.3 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 22 | Q964R1 | 501 | CP6J1_BLAGE Cytochrome P450 6j1 OS=Blattella ... | 222 | 0.0000000000008 | 74.3 | 25 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 23 | P58048 | 506 | C71B8_ARATH Cytochrome P450 71B8 OS=Arabidops... | 284 | 0.000000000001 | 73.6 | 21 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 24 | P10613 | 528 | CP51_CANAL Lanosterol 14-alpha demethylase OS... | 267 | 0.000000000001 | 73.6 | 28 | 42 | GO:0016021; C:integral to membrane; IDA:CGD.::GO:0005624; C:membrane fraction; IDA:CGD.::GO:0005886; C:plasma membrane; IDA:CGD. | | | | | | | | | | GO:0008144; F:drug binding; IDA:CGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IDA:CGD. | | | | | | | | | | GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0006696; P:ergosterol biosynthetic process; IGI:CGD.::GO:0001766; P:membrane raft polarization; IMP:CGD. | 25 | P49602 | 561 | CP51_USTMA Lanosterol 14-alpha demethylase OS... | 340 | 0.000000000004 | 72.4 | 27 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 26 | Q64481 | 504 | CP3AG_MOUSE Cytochrome P450 3A16 OS=Mus muscu... | 218 | 0.000000000004 | 72 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 27 | Q9V5L3 | 589 | C49A1_DROME Probable cytochrome P450 49a1 OS=... | 203 | 0.000000000004 | 72 | 27 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 28 | Q9LTM4 | 502 | C71BJ_ARATH Cytochrome P450 71B19 OS=Arabidop... | 284 | 0.000000000005 | 71.6 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 29 | O18993 | 503 | CP3AL_CALJA Cytochrome P450 3A21 OS=Callithri... | 262 | 0.000000000005 | 71.6 | 25 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 30 | P05183 | 504 | CP3A2_RAT Cytochrome P450 3A2 OS=Rattus norve... | 259 | 0.000000000005 | 71.6 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0032451; F:demethylase activity; IDA:RGD.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IMP:RGD. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:RGD.::GO:0070989; P:oxidative demethylation; IDA:RGD. | 31 | Q9LTM0 | 501 | C71BN_ARATH Cytochrome P450 71B23 OS=Arabidop... | 373 | 0.000000000006 | 71.2 | 21 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | |