| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q84RR2 | 593 | ARI2_ARATH Probable E3 ubiquitin-protein liga... | 182 | 0.001 | 43.9 | 26 | 38 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 32 | D3YYI7 | 515 | RN217_MOUSE Probable E3 ubiquitin-protein lig... | 83 | 0.001 | 43.9 | 34 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 33 | Q9JI90 | 485 | RNF14_MOUSE E3 ubiquitin-protein ligase RNF14... | 198 | 0.001 | 43.9 | 26 | 36 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0019787; F:small conjugating protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | Q4KLT0 | 282 | RN217_XENLA Probable E3 ubiquitin-protein lig... | 83 | 0.003 | 42.4 | 36 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 35 | Q5RFV4 | 293 | R1441_DANRE Probable E3 ubiquitin-protein lig... | 199 | 0.003 | 42.4 | 24 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 36 | Q8TC41 | 275 | RN217_HUMAN Probable E3 ubiquitin-protein lig... | 83 | 0.003 | 42.4 | 34 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 37 | Q9UBS8 | 474 | RNF14_HUMAN E3 ubiquitin-protein ligase RNF14... | 198 | 0.003 | 42.7 | 26 | 37 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0019787; F:small conjugating protein ligase activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0016567; P:protein ubiquitination; IEP:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:UniProtKB.::GO:0032355; P:response to estradiol stimulus; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 38 | Q9SKC2 | 542 | ARI11_ARATH Probable E3 ubiquitin-protein lig... | 182 | 0.005 | 42.4 | 26 | 37 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 39 | Q54CX4 | 903 | Y5521_DICDI Uncharacterized protein DDB_G0292... | 214 | 0.007 | 42 | 21 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 40 | A4IIY1 | 292 | R144A_XENTR Probable E3 ubiquitin-protein lig... | 193 | 0.016 | 40 | 24 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 41 | Q8BKD6 | 301 | R144B_MOUSE E3 ubiquitin-protein ligase RNF14... | 177 | 0.021 | 40 | 26 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB. | 42 | Q9WVS6 | 464 | PRKN2_MOUSE E3 ubiquitin-protein ligase parki... | 247 | 0.024 | 40 | 25 | 36 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042417; P:dopamine metabolic process; IMP:MGI.::GO:0051583; P:dopamine uptake; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042415; P:norepinephrine metabolic process; IMP:MGI.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:MGI.::GO:0001964; P:startle response; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 43 | Q7Z419 | 303 | R144B_HUMAN E3 ubiquitin-protein ligase RNF14... | 176 | 0.024 | 39.7 | 26 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IC:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 44 | A2A7Q9 | 732 | RN19B_MOUSE E3 ubiquitin-protein ligase RNF19... | 189 | 0.046 | 39.3 | 26 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 45 | O60260 | 465 | PRKN2_HUMAN E3 ubiquitin-protein ligase parki... | 250 | 0.047 | 38.9 | 24 | 36 | GO:0016235; C:aggresome; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0051087; F:chaperone binding; IPI:BHF-UCL.::GO:0030165; F:PDZ domain binding; IPI:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070842; P:aggresome assembly; IMP:BHF-UCL.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0000422; P:mitochondrion degradation; IMP:UniProtKB.::GO:0032232; P:negative regulation of actin filament bundle assembly; IDA:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IDA:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IDA:BHF-UCL.::GO:0070997; P:neuron death; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 46 | Q6ZMZ0 | 732 | RN19B_HUMAN E3 ubiquitin-protein ligase RNF19... | 189 | 0.05 | 39.3 | 26 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 47 | Q9JK66 | 465 | PRKN2_RAT E3 ubiquitin-protein ligase parkin ... | 248 | 0.053 | 38.9 | 24 | 35 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0008021; C:synaptic vesicle; IDA:RGD. | | | | | | | | | | GO:0032403; F:protein complex binding; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0070997; P:neuron death; ISS:UniProtKB.::GO:0042551; P:neuron maturation; IEP:RGD.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0010506; P:regulation of autophagy; ISS:UniProtKB.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0006986; P:response to unfolded protein; IDA:RGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 48 | P50876 | 292 | R144A_HUMAN Probable E3 ubiquitin-protein lig... | 197 | 0.061 | 38.5 | 24 | 36 | GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 49 | Q6GZQ2 | 324 | 073L_FRG3G Uncharacterized protein 073L OS=Fr... | 76 | 0.073 | 38.1 | 37 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 50 | Q1L8L6 | 701 | RN19B_DANRE E3 ubiquitin-protein ligase RNF19... | 185 | 0.092 | 38.1 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 51 | Q925F3 | 292 | R144A_MOUSE Probable E3 ubiquitin-protein lig... | 197 | 0.094 | 37.7 | 23 | 36 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 52 | Q96EP0 | 1072 | RNF31_HUMAN E3 ubiquitin-protein ligase RNF31... | 208 | 0.094 | 38.5 | 27 | 38 | GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0071797; C:LUBAC complex; IDA:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; ISS:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB. | 53 | A5PK27 | 304 | R144B_BOVIN E3 ubiquitin-protein ligase RNF14... | 174 | 0.11 | 37.7 | 26 | 38 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB. | 54 | Q62921 | 508 | HOIL1_RAT RanBP-type and C3HC4-type zinc fing... | 210 | 0.14 | 37.7 | 23 | 39 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 55 | Q94981 | 503 | ARI1_DROME Protein ariadne-1 OS=Drosophila me... | 91 | 0.2 | 37 | 29 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 56 | Q6DH94 | 293 | R1442_DANRE Probable E3 ubiquitin-protein lig... | 203 | 0.24 | 36.6 | 26 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 57 | Q9WUB0 | 508 | HOIL1_MOUSE RanBP-type and C3HC4-type zinc fi... | 211 | 0.27 | 36.6 | 25 | 41 | GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB. | 58 | Q04638 | 464 | ITT1_YEAST Translation termination inhibitor ... | 54 | 0.27 | 36.6 | 41 | 57 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006449; P:regulation of translational termination; IMP:SGD. | 59 | Q924T7 | 1066 | RNF31_MOUSE E3 ubiquitin-protein ligase RNF31... | 183 | 0.28 | 37 | 28 | 38 | GO:0035631; C:CD40 receptor complex; IDA:BHF-UCL.::GO:0005829; C:cytosol; IDA:MGI.::GO:0009898; C:internal side of plasma membrane; IDA:BHF-UCL.::GO:0071797; C:LUBAC complex; ISS:UniProtKB. | | | | | | | | | | GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0023035; P:CD40 signaling pathway; IMP:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0097039; P:protein linear polyubiquitination; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB. | 60 | Q80VI1 | 734 | TRI56_MOUSE E3 ubiquitin-protein ligase TRIM5... | 115 | 0.86 | 35 | 30 | 37 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0032608; P:interferon-beta production; IMP:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0034340; P:response to type I interferon; IDA:UniProtKB. | 61 | Q9NWF9 | 866 | RN216_HUMAN E3 ubiquitin-protein ligase RNF21... | 31 | 1 | 35 | 45 | 61 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0050691; P:regulation of defense response to virus by host; IDA:UniProtKB.::GO:0032648; P:regulation of interferon-beta production; IDA:UniProtKB. |
