rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q00IB7 | 1433 | PKHH1_DANRE Pleckstrin homology domain-contai... | 96 | 0.0000004 | 58.9 | 30 | 55 | GO:0005856; C:cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0001569; P:patterning of blood vessels; IMP:ZFIN. | 32 | Q8N4B1 | 249 | SESQ1_HUMAN Sesquipedalian-1 OS=Homo sapiens ... | 119 | 0.000003 | 53.9 | 31 | 50 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0001881; P:receptor recycling; IMP:UniProtKB.::GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB. | 33 | P64866 | 414 | Y1551_MYCBO Uncharacterized glycosyltransfera... | 83 | 0.000004 | 54.7 | 35 | 53 | | | | | | | | | | | GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. | | | | | | | | | | GO:0030259; P:lipid glycosylation; IEA:InterPro. | 34 | P64865 | 414 | Y1524_MYCTU Uncharacterized glycosyltransfera... | 83 | 0.000004 | 54.7 | 35 | 53 | | | | | | | | | | | GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. | | | | | | | | | | GO:0030259; P:lipid glycosylation; IEA:InterPro. | 35 | Q3KR56 | 723 | GRM1A_RAT GRAM domain-containing protein 1A O... | 32 | 0.11 | 40.8 | 47 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 36 | Q8VEF1 | 722 | GRM1A_MOUSE GRAM domain-containing protein 1A... | 32 | 0.11 | 40.8 | 47 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 37 | Q96CP6 | 724 | GRM1A_HUMAN GRAM domain-containing protein 1A... | 32 | 0.11 | 40.8 | 47 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 38 | P54644 | 444 | KRAC_DICDI RAC family serine/threonine-protei... | 145 | 0.00003 | 52 | 28 | 43 | GO:0005938; C:cell cortex; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase. | 39 | Q6ZT07 | 1266 | TBCD9_HUMAN TBC1 domain family member 9 OS=Ho... | 46 | 1.9 | 37 | 35 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 40 | Q3KR37 | 738 | GRM1B_HUMAN GRAM domain-containing protein 1B... | 33 | 0.16 | 40.4 | 45 | 73 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 41 | Q80TI0 | 738 | GRM1B_MOUSE GRAM domain-containing protein 1B... | 33 | 0.16 | 40.4 | 45 | 73 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 42 | Q8IYS0 | 662 | GRM1C_HUMAN GRAM domain-containing protein 1C... | 32 | 0.12 | 40.8 | 44 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 43 | Q5RC33 | 662 | GRM1C_PONAB GRAM domain-containing protein 1C... | 32 | 0.12 | 40.8 | 44 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 44 | P28818 | 1244 | RGRF1_RAT Ras-specific guanine nucleotide-rel... | 133 | 0.0001 | 50.8 | 27 | 46 | GO:0005829; C:cytosol; ISS:HGNC.::GO:0030426; C:growth cone; ISS:HGNC. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; TAS:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:HGNC.::GO:0031175; P:neuron projection development; ISS:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0035020; P:regulation of Rac protein signal transduction; ISS:HGNC.::GO:0048167; P:regulation of synaptic plasticity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 45 | B0R0W9 | 1108 | TBC8B_DANRE TBC1 domain family member 8B OS=D... | 107 | 0.81 | 38.1 | 28 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 46 | Q9W5D0 | 1820 | Y34F_DROME Uncharacterized protein CG42248 OS... | 104 | 0.0002 | 50.1 | 27 | 50 | GO:0005856; C:cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 47 | Q8WZ64 | 1704 | ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 108 | 0.0002 | 49.7 | 33 | 47 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 48 | Q08001 | 693 | YL072_YEAST Uncharacterized protein YLR072W O... | 68 | 0.0003 | 49.3 | 34 | 54 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 49 | Q9UH65 | 585 | SWP70_HUMAN Switch-associated protein 70 OS=H... | 96 | 0.0003 | 49.3 | 29 | 44 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 50 | Q3UYK3 | 1264 | TBCD9_MOUSE TBC1 domain family member 9 OS=Mu... | 82 | 0.0003 | 49.3 | 33 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 51 | D3ZL52 | 234 | SESQ1_RAT Sesquipedalian-1 OS=Rattus norvegic... | 119 | 0.0004 | 47.4 | 30 | 45 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0055037; C:recycling endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 52 | O42976 | 764 | YGZ7_SCHPO Uncharacterized membrane protein C... | 68 | 0.11 | 40.8 | 26 | 56 | GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 53 | Q66K14 | 1250 | TBC9B_HUMAN TBC1 domain family member 9B OS=H... | 49 | 1.5 | 37.4 | 35 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 54 | P27671 | 1262 | RGRF1_MOUSE Ras-specific guanine nucleotide-r... | 134 | 0.0005 | 48.5 | 27 | 43 | GO:0005829; C:cytosol; IDA:HGNC.::GO:0030426; C:growth cone; IDA:HGNC. | | | | | | | | | | GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IDA:HGNC.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:MGI.::GO:0035020; P:regulation of Rac protein signal transduction; IDA:HGNC.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 55 | P64870 | 426 | Y1553_MYCBO Uncharacterized protein Mb1553c O... | 49 | 0.0006 | 47.8 | 47 | 61 | | | | | | | | | | | GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. | | | | | | | | | | GO:0030259; P:lipid glycosylation; IEA:InterPro. | 56 | P64869 | 426 | Y1526_MYCTU Uncharacterized protein Rv1526c/M... | 49 | 0.0006 | 47.8 | 47 | 61 | | | | | | | | | | | GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. | | | | | | | | | | GO:0030259; P:lipid glycosylation; IEA:InterPro. | 57 | Q5SVR0 | 1263 | TBC9B_MOUSE TBC1 domain family member 9B OS=M... | 49 | 1.1 | 37.7 | 35 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. | | | | | | | | | | | 58 | P0C1G6 | 585 | SWP70_BOVIN Switch-associated protein 70 OS=B... | 97 | 0.001 | 47.4 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | | 59 | Q4LDD4 | 1452 | ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 107 | 0.11 | 41.2 | 27 | 48 | GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 60 | Q6A028 | 585 | SWP70_MOUSE Switch-associated protein 70 OS=M... | 96 | 0.002 | 46.6 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0045190; P:isotype switching; IDA:MGI. | 61 | Q16760 | 1214 | DGKD_HUMAN Diacylglycerol kinase delta OS=Hom... | 101 | 0.002 | 47 | 29 | 48 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019992; F:diacylglycerol binding; NAS:UniProtKB.::GO:0004143; F:diacylglycerol kinase activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IDA:MGI.::GO:0042803; F:protein homodimerization activity; IDA:MGI. | | | | | | | | | | GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; NAS:UniProtKB.::GO:0016049; P:cell growth; NAS:UniProtKB.::GO:0046339; P:diacylglycerol metabolic process; NAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; NAS:UniProtKB.::GO:0007275; P:multicellular organismal development; NAS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051260; P:protein homooligomerization; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0010033; P:response to organic substance; IDA:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB. |