rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q6MGB6 | 406 | RING1_RAT E3 ubiquitin-protein ligase RING1 O... | 84 | 0.0003 | 47 | 32 | 48 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 32 | O35730 | 406 | RING1_MOUSE E3 ubiquitin-protein ligase RING1... | 87 | 0.0003 | 47 | 32 | 49 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0001739; C:sex chromatin; IDA:MGI.::GO:0000151; C:ubiquitin ligase complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0048593; P:camera-type eye morphogenesis; IGI:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 33 | Q06587 | 406 | RING1_HUMAN E3 ubiquitin-protein ligase RING1... | 64 | 0.0004 | 46.6 | 36 | 52 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0035518; P:histone H2A monoubiquitination; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 34 | Q5TJF3 | 406 | RING1_CANFA E3 ubiquitin-protein ligase RING1... | 64 | 0.0004 | 46.2 | 36 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 35 | Q810I1 | 483 | TRI50_RAT E3 ubiquitin-protein ligase TRIM50 ... | 73 | 0.0004 | 46.2 | 33 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 36 | P19474 | 475 | RO52_HUMAN E3 ubiquitin-protein ligase TRIM21... | 83 | 0.0005 | 46.2 | 30 | 54 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; IMP:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB. | 37 | Q3U827 | 592 | RN180_MOUSE E3 ubiquitin-protein ligase RNF18... | 99 | 0.0005 | 46.2 | 27 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031227; C:intrinsic to endoplasmic reticulum membrane; IDA:MGI.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0031624; F:ubiquitin conjugating enzyme binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:MGI. | 38 | Q9BVG3 | 475 | TRI62_HUMAN Tripartite motif-containing prote... | 50 | 0.0005 | 45.8 | 38 | 56 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 39 | Q80V85 | 475 | TRI62_MOUSE Tripartite motif-containing prote... | 50 | 0.0006 | 45.8 | 38 | 56 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 40 | A2T6X5 | 377 | RING1_PANTR E3 ubiquitin-protein ligase RING1... | 64 | 0.0006 | 45.8 | 36 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 41 | A1YFY1 | 377 | RING1_PANPA E3 ubiquitin-protein ligase RING1... | 64 | 0.0006 | 45.8 | 36 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 42 | Q8WMN5 | 377 | RING1_MACMU E3 ubiquitin-protein ligase RING1... | 64 | 0.0006 | 45.8 | 36 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 43 | A1YER5 | 377 | RING1_GORGO E3 ubiquitin-protein ligase RING1... | 64 | 0.0006 | 45.8 | 36 | 52 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0035102; C:PRC1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 44 | Q7ZUK0 | 364 | RN146_DANRE E3 ubiquitin-protein ligase rnf14... | 43 | 0.0006 | 45.4 | 44 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 45 | Q9VB08 | 435 | RING1_DROME E3 ubiquitin-protein ligase RING1... | 67 | 0.0006 | 45.8 | 36 | 51 | GO:0008278; C:cohesin complex; IDA:UniProtKB.::GO:0035102; C:PRC1 complex; TAS:FlyBase. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006342; P:chromatin silencing; IDA:UniProtKB.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0022008; P:neurogenesis; IMP:FlyBase.::GO:0030713; P:ovarian follicle cell stalk formation; IMP:FlyBase.::GO:0045498; P:sex comb development; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 46 | Q810I2 | 483 | TRI50_MOUSE E3 ubiquitin-protein ligase TRIM5... | 73 | 0.0007 | 45.8 | 33 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 47 | Q95KF1 | 232 | RN125_MACFA E3 ubiquitin-protein ligase RNF12... | 45 | 0.001 | 44.3 | 42 | 56 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 48 | Q8R0K2 | 507 | TRI31_MOUSE E3 ubiquitin-protein ligase TRIM3... | 48 | 0.001 | 45.1 | 35 | 63 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 49 | Q96EQ8 | 232 | RN125_HUMAN E3 ubiquitin-protein ligase RNF12... | 45 | 0.001 | 44.3 | 42 | 56 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome. | 50 | Q4PGG5 | 1387 | RAD5_USTMA DNA repair protein RAD5 OS=Ustilag... | 72 | 0.001 | 45.4 | 39 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 51 | Q1L721 | 222 | RN138_XENLA E3 ubiquitin-protein ligase RNF13... | 49 | 0.001 | 43.9 | 41 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 52 | C0HBT3 | 349 | RN146_SALSA E3 ubiquitin-protein ligase rnf14... | 43 | 0.002 | 43.9 | 44 | 56 | GO:0005829; C:cytosol; ISS:UniProtKB. | | | | | | | | | | GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 53 | Q8BFW4 | 522 | TRI65_MOUSE Tripartite motif-containing prote... | 45 | 0.002 | 44.3 | 40 | 49 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 54 | Q8RXD4 | 941 | BRCA1_ARATH Protein BREAST CANCER SUSCEPTIBIL... | 40 | 0.002 | 44.3 | 43 | 58 | GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006310; P:DNA recombination; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0010332; P:response to gamma radiation; IEP:TAIR. | 55 | P40072 | 274 | SLX8_YEAST E3 ubiquitin-protein ligase comple... | 58 | 0.002 | 43.5 | 38 | 50 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 56 | Q86XT4 | 487 | TRI50_HUMAN E3 ubiquitin-protein ligase TRIM5... | 69 | 0.002 | 43.9 | 32 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 57 | Q7TMI3 | 803 | UHRF2_MOUSE E3 ubiquitin-protein ligase UHRF2... | 80 | 0.003 | 43.9 | 35 | 48 | GO:0005720; C:nuclear heterochromatin; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; ISS:HGNC.::GO:0008283; P:cell proliferation; ISS:HGNC.::GO:0071158; P:positive regulation of cell cycle arrest; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:HGNC.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:HGNC. | 58 | Q9NS56 | 1045 | TOPRS_HUMAN E3 ubiquitin-protein ligase Topor... | 62 | 0.004 | 43.5 | 37 | 58 | GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB. | | | | | | | | | | GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0044547; F:DNA topoisomerase binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0051457; P:maintenance of protein location in nucleus; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB. | 59 | Q0IIM1 | 573 | RN168_BOVIN E3 ubiquitin-protein ligase RNF16... | 83 | 0.004 | 43.5 | 27 | 45 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 60 | Q5RAK3 | 592 | RN180_PONAB E3 ubiquitin-protein ligase RNF18... | 82 | 0.004 | 43.5 | 27 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 61 | Q80Z37 | 1033 | TOPRS_MOUSE E3 ubiquitin-protein ligase Topor... | 62 | 0.004 | 43.5 | 37 | 58 | GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IDA:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IDA:MGI. |