| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
721 | Q09898 | 607 | SID2_SCHPO Serine/threonine-protein kinase si... | 75 | 0.026 | 39.7 | 33 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0034973; C:Sid2-Mob1 complex; IPI:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0061167; P:maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031028; P:septation initiation signaling cascade; IMP:PomBase. | 722 | Q54IP4 | 653 | SHKB_DICDI Dual specificity protein kinase sh... | 139 | 0.026 | 39.7 | 22 | 45 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 723 | Q7PLI7 | 748 | DCLK_DROME Serine/threonine-protein kinase CG... | 177 | 0.026 | 39.7 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 724 | O60674 | 1132 | JAK2_HUMAN Tyrosine-protein kinase JAK2 OS=Ho... | 225 | 0.026 | 39.7 | 24 | 44 | GO:0005901; C:caveola; ISS:BHF-UCL.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0031904; C:endosome lumen; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0035401; F:histone kinase activity (H3-Y41 specific); IDA:UniProtKB.::GO:0005143; F:interleukin-12 receptor binding; ISS:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; IDA:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0030041; P:actin filament polymerization; NAS:BHF-UCL.::GO:0008636; P:activation of caspase activity by protein phosphorylation; ISS:BHF-UCL.::GO:0042977; P:activation of JAK2 kinase activity; ISS:UniProtKB.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0006928; P:cellular component movement; TAS:ProtInc.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0035722; P:interleukin-12-mediated signaling pathway; IDA:BHF-UCL.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; ISS:UniProtKB.::GO:0061180; P:mammary gland epithelium development; ISS:BHF-UCL.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; ISS:BHF-UCL.::GO:0043392; P:negative regulation of DNA binding; ISS:BHF-UCL.::GO:0010811; P:positive regulation of cell-substrate adhesion; IDA:BHF-UCL.::GO:0060399; P:positive regulation of growth hormone receptor signaling pathway; ISS:BHF-UCL.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0042523; P:positive regulation of tyrosine phosphorylation of Stat5 protein; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0046677; P:response to antibiotic; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; ISS:BHF-UCL.::GO:0007262; P:STAT protein import into nucleus; ISS:BHF-UCL.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IDA:BHF-UCL. | 725 | Q2LYK3 | 777 | PLK4_DROPS Serine/threonine-protein kinase PL... | 199 | 0.026 | 39.7 | 22 | 46 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 726 | Q9GT24 | 706 | ZYG1_CAEEL Probable serine/threonine-protein ... | 69 | 0.026 | 39.7 | 29 | 52 | GO:0005814; C:centriole; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IMP:WormBase.::GO:0007099; P:centriole replication; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008104; P:protein localization; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0051225; P:spindle assembly; IMP:WormBase. | 727 | P13234 | 474 | KCC4_RAT Calcium/calmodulin-dependent protein... | 103 | 0.026 | 39.7 | 30 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB. | 728 | O15264 | 365 | MK13_HUMAN Mitogen-activated protein kinase 1... | 89 | 0.026 | 39.3 | 26 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006970; P:response to osmotic stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 729 | P0C8M8 | 626 | CCR1_MAIZE Probable serine/threonine-protein ... | 107 | 0.026 | 39.7 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 730 | Q16620 | 822 | NTRK2_HUMAN BDNF/NT-3 growth factors receptor... | 202 | 0.026 | 39.7 | 23 | 44 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048403; F:brain-derived neurotrophic factor binding; ISS:UniProtKB.::GO:0060175; F:brain-derived neurotrophic factor-activated receptor activity; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0007190; P:activation of adenylate cyclase activity; TAS:Reactome.::GO:0021954; P:central nervous system neuron development; ISS:UniProtKB.::GO:0021987; P:cerebral cortex development; ISS:UniProtKB.::GO:0007612; P:learning; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0050772; P:positive regulation of axonogenesis; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB. | 731 | Q924I2 | 873 | M4K3_RAT Mitogen-activated protein kinase kin... | 68 | 0.026 | 39.7 | 32 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 732 | Q8CIN4 | 524 | PAK2_MOUSE Serine/threonine-protein kinase PA... | 137 | 0.027 | 39.7 | 26 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 733 | Q5KQF5 | 451 | CIPKM_ORYSJ CBL-interacting protein kinase 22... | 108 | 0.027 | 39.7 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 734 | Q9H0K1 | 926 | SIK2_HUMAN Serine/threonine-protein kinase SI... | 102 | 0.027 | 39.7 | 28 | 49 | GO:0005794; C:Golgi apparatus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; ISS:UniProtKB. | 735 | O42127 | 802 | FGFR3_XENLA Fibroblast growth factor receptor... | 254 | 0.027 | 39.7 | 24 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 736 | Q14289 | 1009 | FAK2_HUMAN Protein-tyrosine kinase 2-beta OS=... | 231 | 0.027 | 39.7 | 25 | 42 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0004871; F:signal transducer activity; NAS:ProtInc. | | | | | | | | | | GO:0042976; P:activation of Janus kinase activity; IMP:UniProtKB.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0070098; P:chemokine-mediated signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0002315; P:marginal zone B cell differentiation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0030502; P:negative regulation of bone mineralization; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:UniProtKB.::GO:0043267; P:negative regulation of potassium ion transport; IDA:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:2000538; P:positive regulation of B cell chemotaxis; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB.::GO:0032960; P:regulation of inositol trisphosphate biosynthetic process; ISS:UniProtKB.::GO:0010758; P:regulation of macrophage chemotaxis; ISS:UniProtKB.::GO:2000058; P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0007172; P:signal complex assembly; TAS:ProtInc.::GO:0002040; P:sprouting angiogenesis; ISS:UniProtKB.::GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IMP:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 737 | Q5R8X7 | 966 | M3K13_PONAB Mitogen-activated protein kinase ... | 155 | 0.027 | 39.7 | 23 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0007254; P:JNK cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 738 | Q64303 | 524 | PAK2_RAT Serine/threonine-protein kinase PAK ... | 137 | 0.027 | 39.7 | 26 | 46 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 739 | O18735 | 1259 | ERBB2_CANFA Receptor tyrosine-protein kinase ... | 157 | 0.027 | 39.7 | 22 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IEA:InterPro.::GO:0001042; F:RNA polymerase I core binding; ISS:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045943; P:positive regulation of transcription from RNA polymerase I promoter; ISS:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; ISS:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 740 | Q42396 | 490 | CDPKC_ARATH Calcium-dependent protein kinase ... | 105 | 0.028 | 39.7 | 30 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 741 | Q99JP0 | 894 | M4K3_MOUSE Mitogen-activated protein kinase k... | 68 | 0.028 | 39.7 | 32 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 742 | Q1ZXI5 | 1350 | Y1558_DICDI Probable serine/threonine-protein... | 63 | 0.028 | 39.7 | 32 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 743 | Q6PAD2 | 944 | PLK4_XENLA Serine/threonine-protein kinase PL... | 213 | 0.029 | 39.7 | 23 | 45 | GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB. | 744 | Q9N272 | 365 | MK13_PANTR Mitogen-activated protein kinase 1... | 89 | 0.029 | 39.3 | 26 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 745 | Q63604 | 821 | NTRK2_RAT BDNF/NT-3 growth factors receptor O... | 190 | 0.029 | 39.7 | 24 | 45 | GO:0009986; C:cell surface; IDA:RGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IDA:RGD.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0030426; C:growth cone; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0048786; C:presynaptic active zone; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048403; F:brain-derived neurotrophic factor binding; IDA:UniProtKB.::GO:0060175; F:brain-derived neurotrophic factor-activated receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0021954; P:central nervous system neuron development; ISS:UniProtKB.::GO:0021987; P:cerebral cortex development; ISS:UniProtKB.::GO:0007612; P:learning; ISS:UniProtKB.::GO:0007616; P:long-term memory; IDA:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0050772; P:positive regulation of axonogenesis; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0010628; P:positive regulation of gene expression; ISS:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0051968; P:positive regulation of synaptic transmission, glutamatergic; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050773; P:regulation of dendrite development; IMP:RGD.::GO:0046928; P:regulation of neurotransmitter secretion; IDA:RGD.::GO:0032314; P:regulation of Rac GTPase activity; ISS:UniProtKB.::GO:0010996; P:response to auditory stimulus; IEP:RGD. | 746 | P15209 | 821 | NTRK2_MOUSE BDNF/NT-3 growth factors receptor... | 190 | 0.029 | 39.7 | 24 | 45 | GO:0005829; C:cytosol; IDA:MGI.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0043195; C:terminal button; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0048403; F:brain-derived neurotrophic factor binding; IDA:UniProtKB.::GO:0060175; F:brain-derived neurotrophic factor-activated receptor activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IMP:UniProtKB.::GO:0021954; P:central nervous system neuron development; IMP:UniProtKB.::GO:0021987; P:cerebral cortex development; IMP:UniProtKB.::GO:0007631; P:feeding behavior; IMP:MGI.::GO:0014047; P:glutamate secretion; IPI:MGI.::GO:0007612; P:learning; IMP:UniProtKB.::GO:0060291; P:long-term synaptic potentiation; IMP:UniProtKB.::GO:0042490; P:mechanoreceptor differentiation; IMP:MGI.::GO:2000811; P:negative regulation of anoikis; IDA:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0001764; P:neuron migration; IMP:UniProtKB.::GO:0048709; P:oligodendrocyte differentiation; IMP:UniProtKB.::GO:0048935; P:peripheral nervous system neuron development; IMP:UniProtKB.::GO:0050772; P:positive regulation of axonogenesis; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IMP:UniProtKB.::GO:0043410; P:positive regulation of MAPK cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IDA:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0051896; P:regulation of protein kinase B signaling cascade; IMP:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.::GO:0046548; P:retinal rod cell development; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI. | 747 | P29320 | 983 | EPHA3_HUMAN Ephrin type-A receptor 3 OS=Homo ... | 191 | 0.029 | 39.7 | 23 | 43 | GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005004; F:GPI-linked ephrin receptor activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0097156; P:fasciculation of motor neuron axon; ISS:UniProtKB.::GO:0097155; P:fasciculation of sensory neuron axon; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0032956; P:regulation of actin cytoskeleton organization; IDA:UniProtKB.::GO:0010717; P:regulation of epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; IDA:UniProtKB.::GO:0070507; P:regulation of microtubule cytoskeleton organization; IDA:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; IDA:UniProtKB. | 748 | O61443 | 365 | MK14B_DROME Mitogen-activated protein kinase ... | 79 | 0.029 | 39.3 | 28 | 52 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016909; F:SAP kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0071243; P:cellular response to arsenic-containing substance; IDA:FlyBase.::GO:0071276; P:cellular response to cadmium ion; IDA:FlyBase.::GO:0034614; P:cellular response to reactive oxygen species; IDA:FlyBase.::GO:0042742; P:defense response to bacterium; IMP:FlyBase.::GO:0050832; P:defense response to fungus; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IDA:UniProtKB.::GO:0006955; P:immune response; IMP:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0048082; P:regulation of adult chitin-containing cuticle pigmentation; IGI:FlyBase.::GO:0030510; P:regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0045088; P:regulation of innate immune response; IDA:UniProtKB.::GO:0009408; P:response to heat; IMP:FlyBase.::GO:0042542; P:response to hydrogen peroxide; IMP:FlyBase.::GO:0009651; P:response to salt stress; IMP:FlyBase.::GO:0042594; P:response to starvation; IMP:FlyBase. | 749 | P50545 | 524 | HCK_RAT Tyrosine-protein kinase HCK OS=Rattus... | 133 | 0.03 | 39.3 | 27 | 45 | GO:0005901; C:caveola; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0071801; P:regulation of podosome assembly; ISS:UniProtKB. | 750 | Q9NJU9 | 562 | CDPK3_PLAF7 Calcium-dependent protein kinase ... | 172 | 0.03 | 39.3 | 25 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 751 | Q59S66 | 530 | IPL1_CANAL Spindle assembly checkpoint kinase... | 128 | 0.03 | 39.3 | 23 | 41 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. |
