| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
661 | Q76P07 | 833 | Y7165_DICDI Probable serine/threonine-protein... | 166 | 0.018 | 40.4 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030587; P:sorocarp development; IMP:dictyBase. | 662 | Q9UEE5 | 414 | ST17A_HUMAN Serine/threonine-protein kinase 1... | 106 | 0.018 | 40 | 26 | 50 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB. | 663 | Q7ZZC8 | 944 | NEK9_XENLA Serine/threonine-protein kinase Ne... | 126 | 0.018 | 40.4 | 23 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 664 | Q6FQH2 | 813 | HAL5_CANGA Serine/threonine-protein kinase HA... | 93 | 0.018 | 40.4 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 665 | Q9NYL2 | 800 | MLTK_HUMAN Mitogen-activated protein kinase k... | 109 | 0.018 | 40.4 | 28 | 43 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.::GO:0007050; P:cell cycle arrest; IMP:UniProtKB.::GO:0008219; P:cell death; NAS:UniProtKB.::GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0000077; P:DNA damage checkpoint; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0009314; P:response to radiation; IDA:UniProtKB. | 666 | Q54TA3 | 773 | MRKC_DICDI Probable serine/threonine-protein ... | 174 | 0.018 | 40.4 | 28 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 667 | Q6DE87 | 474 | CHK1_XENLA Serine/threonine-protein kinase Ch... | 73 | 0.018 | 40 | 26 | 51 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035402; F:histone kinase activity (H3-T11 specific); ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045839; P:negative regulation of mitosis; ISS:UniProtKB.::GO:0010569; P:regulation of double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:2000615; P:regulation of histone H3-K9 acetylation; ISS:UniProtKB.::GO:0046602; P:regulation of mitotic centrosome separation; ISS:UniProtKB.::GO:0010767; P:regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage; ISS:UniProtKB. | 668 | P00528 | 552 | SRC64_DROME Tyrosine-protein kinase Src64B OS... | 122 | 0.019 | 40 | 25 | 48 | GO:0045172; C:germline ring canal; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0008302; P:female germline ring canal formation, actin assembly; IMP:FlyBase.::GO:0008335; P:female germline ring canal stabilization; IMP:FlyBase.::GO:0030708; P:germarium-derived female germ-line cyst encapsulation; IMP:FlyBase.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0016319; P:mushroom body development; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030046; P:parallel actin filament bundle assembly; IMP:FlyBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IGI:FlyBase.::GO:0008064; P:regulation of actin polymerization or depolymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase. | 669 | O80345 | 479 | CDKF1_ARATH Cyclin-dependent kinase F-1 OS=Ar... | 119 | 0.019 | 40 | 24 | 45 | GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019912; F:cyclin-dependent protein kinase activating kinase activity; IGI:TAIR.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010078; P:maintenance of root meristem identity; IMP:TAIR.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:TAIR. | 670 | Q8RWC9 | 444 | CIPK1_ARATH CBL-interacting serine/threonine-... | 160 | 0.019 | 40 | 28 | 43 | GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 671 | P97477 | 395 | AURKA_MOUSE Aurora kinase A OS=Mus musculus (... | 123 | 0.019 | 40 | 26 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:MGI. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 672 | Q9SZM3 | 484 | CDPKQ_ARATH Calcium-dependent protein kinase ... | 185 | 0.019 | 40 | 23 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 673 | Q3T0N5 | 366 | MK13_BOVIN Mitogen-activated protein kinase 1... | 89 | 0.019 | 39.7 | 26 | 51 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 674 | P07948 | 512 | LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo... | 133 | 0.02 | 40 | 26 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0070668; P:positive regulation of mast cell proliferation; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0070304; P:positive regulation of stress-activated protein kinase signaling cascade; IDA:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090025; P:regulation of monocyte chemotaxis; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB. | 675 | D3ZSZ3 | 527 | NLK_RAT Serine/threonine-protein kinase NLK O... | 163 | 0.02 | 40 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 676 | O54949 | 527 | NLK_MOUSE Serine/threonine-protein kinase NLK... | 163 | 0.02 | 40 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 677 | Q9UBE8 | 527 | NLK_HUMAN Serine/threonine-protein kinase NLK... | 163 | 0.02 | 40 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0033136; P:serine phosphorylation of STAT3 protein; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 678 | Q9YHZ5 | 310 | PIM2_DANRE Serine/threonine-protein kinase pi... | 213 | 0.02 | 39.7 | 24 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; NAS:ZFIN. | 679 | O35346 | 1055 | FAK1_RAT Focal adhesion kinase 1 OS=Rattus no... | 217 | 0.02 | 40 | 24 | 42 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0014704; C:intercalated disc; IDA:RGD.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016604; C:nuclear body; IDA:RGD.::GO:0005730; C:nucleolus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005178; F:integrin binding; IPI:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030644; P:cellular chloride ion homeostasis; IMP:RGD.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0045444; P:fat cell differentiation; IEP:RGD.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0030336; P:negative regulation of cell migration; IMP:RGD.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; IMP:RGD.::GO:0030307; P:positive regulation of cell growth; IMP:RGD.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:RGD.::GO:0050766; P:positive regulation of phagocytosis; IMP:RGD.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0014911; P:positive regulation of smooth muscle cell migration; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0050806; P:positive regulation of synaptic transmission; IMP:RGD.::GO:0045909; P:positive regulation of vasodilation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0007172; P:signal complex assembly; IEA:InterPro. | 680 | Q99N57 | 648 | RAF1_MOUSE RAF proto-oncogene serine/threonin... | 129 | 0.02 | 40 | 23 | 46 | GO:0005829; C:cytosol; TAS:MGI.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031143; C:pseudopodium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; IPI:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI. | 681 | P06213 | 1382 | INSR_HUMAN Insulin receptor OS=Homo sapiens (... | 117 | 0.02 | 40 | 24 | 47 | GO:0005901; C:caveola; IDA:BHF-UCL.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0005899; C:insulin receptor complex; IMP:BHF-UCL.::GO:0005792; C:microsome; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005525; F:GTP binding; IDA:BHF-UCL.::GO:0043559; F:insulin binding; IDA:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005009; F:insulin-activated receptor activity; IDA:UniProtKB.::GO:0031994; F:insulin-like growth factor I binding; IPI:BHF-UCL.::GO:0031995; F:insulin-like growth factor II binding; IPI:BHF-UCL.::GO:0005159; F:insulin-like growth factor receptor binding; IDA:BHF-UCL.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:UniProtKB.::GO:0051425; F:PTB domain binding; IPI:UniProtKB.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; IDA:BHF-UCL.::GO:0042169; F:SH2 domain binding; IPI:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IMP:BHF-UCL.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0007186; P:G-protein coupled receptor signaling pathway; IDA:BHF-UCL.::GO:0042593; P:glucose homeostasis; IMP:BHF-UCL.::GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IDA:BHF-UCL.::GO:0048639; P:positive regulation of developmental growth; IMP:BHF-UCL.::GO:0045740; P:positive regulation of DNA replication; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IDA:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IDA:BHF-UCL.::GO:0045821; P:positive regulation of glycolysis; IMP:BHF-UCL.::GO:0043410; P:positive regulation of MAPK cascade; IMP:BHF-UCL.::GO:0045840; P:positive regulation of mitosis; IMP:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:BHF-UCL.::GO:0060267; P:positive regulation of respiratory burst; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0051290; P:protein heterotetramerization; IDA:UniProtKB.::GO:0045995; P:regulation of embryonic development; IMP:BHF-UCL.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:BHF-UCL.::GO:0019087; P:transformation of host cell by virus; IMP:BHF-UCL. | 682 | P42680 | 631 | TEC_HUMAN Tyrosine-protein kinase Tec OS=Homo... | 187 | 0.02 | 40 | 21 | 43 | GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0010543; P:regulation of platelet activation; IDA:UniProtKB. | 683 | P32866 | 714 | GPRK2_DROME G protein-coupled receptor kinase... | 109 | 0.021 | 40 | 23 | 44 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004703; F:G-protein coupled receptor kinase activity; IMP:FlyBase. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0002805; P:regulation of antimicrobial peptide biosynthetic process; IMP:FlyBase.::GO:0008589; P:regulation of smoothened signaling pathway; IDA:FlyBase.::GO:0008592; P:regulation of Toll signaling pathway; IGI:FlyBase.::GO:0007224; P:smoothened signaling pathway; IMP:FlyBase.::GO:0038032; P:termination of G-protein coupled receptor signaling pathway; IEA:InterPro. | 684 | O22040 | 666 | ANP1_ARATH Mitogen-activated protein kinase k... | 159 | 0.021 | 40 | 23 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR. | 685 | F1NBT0 | 969 | STK10_CHICK Serine/threonine-protein kinase 1... | 105 | 0.021 | 40 | 25 | 51 | GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; ISS:UniProtKB. | 686 | Q9QYZ5 | 504 | SMK3_MOUSE Sperm motility kinase 3 OS=Mus mus... | 157 | 0.021 | 40 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 687 | P34152 | 1090 | FAK1_MOUSE Focal adhesion kinase 1 OS=Mus mus... | 217 | 0.021 | 40 | 23 | 42 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:MGI.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:MGI.::GO:0043542; P:endothelial cell migration; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0040023; P:establishment of nucleus localization; IDA:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:MGI.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0050771; P:negative regulation of axonogenesis; IMP:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0051964; P:negative regulation of synapse assembly; IMP:MGI.::GO:0001764; P:neuron migration; IDA:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0045860; P:positive regulation of protein kinase activity; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0007172; P:signal complex assembly; IEA:InterPro.::GO:0001570; P:vasculogenesis; IMP:MGI. | 688 | Q8SQZ4 | 405 | YAK1_ENCCU Probable dual specificity protein ... | 100 | 0.021 | 39.7 | 25 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 689 | P24604 | 630 | TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus ... | 192 | 0.021 | 40 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 690 | O73798 | 1358 | IGF1R_XENLA Insulin-like growth factor 1 rece... | 107 | 0.022 | 40 | 24 | 50 | GO:0005887; C:integral to plasma membrane; IC:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005520; F:insulin-like growth factor binding; IDA:UniProtKB.::GO:0005010; F:insulin-like growth factor-activated receptor activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0043548; F:phosphatidylinositol 3-kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001556; P:oocyte maturation; IEP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; ISS:UniProtKB. | 691 | P18654 | 740 | KS6A3_MOUSE Ribosomal protein S6 kinase alpha... | 96 | 0.59 | 35.4 | 26 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0032496; P:response to lipopolysaccharide; IMP:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB. |
