| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
571 | Q8N5S9 | 505 | KKCC1_HUMAN Calcium/calmodulin-dependent prot... | 105 | 0.016 | 39.3 | 24 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007268; P:synaptic transmission; TAS:Reactome. | 572 | Q696W0 | 2995 | SPEG_DANRE Striated muscle preferentially exp... | 104 | 0.016 | 39.3 | 30 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:ZFIN. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007517; P:muscle organ development; ISS:ZFIN. | 573 | Q9FY48 | 1625 | KEG_ARATH E3 ubiquitin-protein ligase KEG OS=... | 93 | 0.016 | 39.3 | 32 | 43 | GO:0005769; C:early endosome; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043621; F:protein self-association; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0006952; P:defense response; IMP:TAIR.::GO:0048589; P:developmental growth; IMP:TAIR.::GO:0009788; P:negative regulation of abscisic acid mediated signaling pathway; IMP:TAIR. | 574 | Q32MK0 | 819 | MYLK3_HUMAN Putative myosin light chain kinas... | 86 | 0.017 | 39.3 | 31 | 45 | GO:0005829; C:cytosol; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:BHF-UCL.::GO:0004687; F:myosin light chain kinase activity; ISS:BHF-UCL. | | | | | | | | | | GO:0055003; P:cardiac myofibril assembly; ISS:BHF-UCL.::GO:0071347; P:cellular response to interleukin-1; IMP:BHF-UCL.::GO:0060298; P:positive regulation of sarcomere organization; ISS:BHF-UCL.::GO:0002528; P:regulation of vascular permeability involved in acute inflammatory response; IMP:BHF-UCL.::GO:0045214; P:sarcomere organization; ISS:BHF-UCL.::GO:0048769; P:sarcomerogenesis; ISS:BHF-UCL. | 575 | P63185 | 526 | SRC_RSVSE Tyrosine-protein kinase transformin... | 84 | 0.017 | 38.9 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 576 | P04048 | 370 | KIT_FSVHZ Tyrosine-protein kinase transformin... | 99 | 0.017 | 38.9 | 28 | 48 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 577 | Q6DGS3 | 554 | KC2D2_DANRE Calcium/calmodulin-dependent prot... | 138 | 0.017 | 38.9 | 25 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 578 | Q5RDG7 | 819 | MYLK3_PONAB Putative myosin light chain kinas... | 86 | 0.017 | 39.3 | 31 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | | 579 | P00545 | 978 | KFMS_FSVMD Tyrosine-protein kinase transformi... | 99 | 0.017 | 39.3 | 30 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 580 | P13369 | 980 | CSF1R_FELCA Macrophage colony-stimulating fac... | 99 | 0.018 | 39.3 | 30 | 45 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019955; F:cytokine binding; ISS:UniProtKB.::GO:0005011; F:macrophage colony-stimulating factor receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0045124; P:regulation of bone resorption; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0031529; P:ruffle organization; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB. | 581 | P31693 | 523 | SRC_RSVPA Tyrosine-protein kinase transformin... | 84 | 0.018 | 38.9 | 30 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 582 | Q91909 | 954 | KIT_XENLA Mast/stem cell growth factor recept... | 101 | 0.019 | 38.9 | 28 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 583 | P22182 | 812 | FGFR1_XENLA Fibroblast growth factor receptor... | 79 | 0.019 | 38.9 | 32 | 46 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. | 584 | P35918 | 1367 | VGFR2_MOUSE Vascular endothelial growth facto... | 111 | 0.019 | 39.3 | 29 | 48 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005769; C:early endosome; IDA:BHF-UCL.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019838; F:growth factor binding; IEA:InterPro.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0060837; P:blood vessel endothelial cell differentiation; TAS:DFLAT.::GO:0035584; P:calcium-mediated signaling using intracellular calcium source; ISS:UniProtKB.::GO:0002042; P:cell migration involved in sprouting angiogenesis; IMP:BHF-UCL.::GO:0035162; P:embryonic hemopoiesis; IMP:UniProtKB.::GO:0003157; P:endocardium development; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0038083; P:peptidyl-tyrosine autophosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IDA:DFLAT.::GO:0030513; P:positive regulation of BMP signaling pathway; IDA:DFLAT.::GO:0010595; P:positive regulation of endothelial cell migration; TAS:DFLAT.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; TAS:DFLAT.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; IMP:UniProtKB. | 585 | Q9LDI3 | 446 | CIPKO_ARATH CBL-interacting serine/threonine-... | 172 | 0.019 | 38.9 | 23 | 37 | GO:0009705; C:plant-type vacuole membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 586 | P07333 | 972 | CSF1R_HUMAN Macrophage colony-stimulating fac... | 99 | 0.02 | 38.9 | 30 | 45 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0043235; C:receptor complex; ISS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019955; F:cytokine binding; IDA:UniProtKB.::GO:0005011; F:macrophage colony-stimulating factor receptor activity; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0045217; P:cell-cell junction maintenance; IMP:UniProtKB.::GO:0036006; P:cellular response to macrophage colony-stimulating factor stimulus; IMP:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; IMP:UniProtKB.::GO:0006954; P:inflammatory response; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0030225; P:macrophage differentiation; TAS:UniProtKB.::GO:0060603; P:mammary gland duct morphogenesis; TAS:UniProtKB.::GO:0030224; P:monocyte differentiation; TAS:UniProtKB.::GO:0030316; P:osteoclast differentiation; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0046488; P:phosphatidylinositol metabolic process; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0090197; P:positive regulation of chemokine secretion; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0061098; P:positive regulation of protein tyrosine kinase activity; IMP:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0045124; P:regulation of bone resorption; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0031529; P:ruffle organization; ISS:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; ISS:UniProtKB. | 587 | A7F0W2 | 951 | ATG1_SCLS1 Serine/threonine-protein kinase AT... | 86 | 0.02 | 38.9 | 30 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 588 | P42679 | 507 | MATK_HUMAN Megakaryocyte-associated tyrosine-... | 80 | 0.02 | 38.9 | 28 | 45 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc. | 589 | Q63796 | 888 | M3K12_RAT Mitogen-activated protein kinase ki... | 139 | 0.021 | 38.9 | 26 | 42 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0016572; P:histone phosphorylation; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 590 | P22607 | 806 | FGFR3_HUMAN Fibroblast growth factor receptor... | 80 | 0.021 | 38.9 | 30 | 46 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IMP:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0070977; P:bone maturation; ISS:BHF-UCL.::GO:0002062; P:chondrocyte differentiation; TAS:UniProtKB.::GO:0035988; P:chondrocyte proliferation; TAS:UniProtKB.::GO:0003416; P:endochondral bone growth; TAS:UniProtKB.::GO:0001958; P:endochondral ossification; TAS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0007259; P:JAK-STAT cascade; TAS:ProtInc.::GO:0000165; P:MAPK cascade; TAS:ProtInc.::GO:0048640; P:negative regulation of developmental growth; ISS:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.::GO:0042511; P:positive regulation of tyrosine phosphorylation of Stat1 protein; IMP:UniProtKB.::GO:0042517; P:positive regulation of tyrosine phosphorylation of Stat3 protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB. | 591 | P34314 | 965 | TLK1_CAEEL Serine/threonine-protein kinase to... | 95 | 0.021 | 38.9 | 25 | 44 | GO:0000790; C:nuclear chromatin; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IMP:UniProtKB. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0045860; P:positive regulation of protein kinase activity; IDA:WormBase.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0006479; P:protein methylation; IMP:WormBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 592 | P07948 | 512 | LYN_HUMAN Tyrosine-protein kinase Lyn OS=Homo... | 84 | 0.021 | 38.9 | 27 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; TAS:Reactome.::GO:0004716; F:receptor signaling protein tyrosine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0071300; P:cellular response to retinoic acid; IMP:BHF-UCL.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0050777; P:negative regulation of immune response; TAS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0070668; P:positive regulation of mast cell proliferation; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:BHF-UCL.::GO:0070304; P:positive regulation of stress-activated protein kinase signaling cascade; IDA:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090025; P:regulation of monocyte chemotaxis; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB. | 593 | P03949 | 1224 | ABL1_CAEEL Tyrosine-protein kinase abl-1 OS=C... | 84 | 0.021 | 38.9 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; IPI:WormBase. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0000077; P:DNA damage checkpoint; IGI:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.::GO:0030336; P:negative regulation of cell migration; IGI:WormBase.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IMP:WormBase.::GO:0060101; P:negative regulation of phagocytosis, engulfment; IGI:WormBase.::GO:0010212; P:response to ionizing radiation; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. | 594 | Q6P3R8 | 708 | NEK5_HUMAN Serine/threonine-protein kinase Ne... | 88 | 0.021 | 38.9 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 595 | Q6AVM3 | 516 | CCAMK_ORYSJ Calcium and calcium/calmodulin-de... | 85 | 0.022 | 38.5 | 31 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 596 | P42686 | 505 | SRK1_SPOLA Tyrosine-protein kinase isoform SR... | 78 | 0.023 | 38.5 | 27 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 597 | Q54MH0 | 749 | FHKD_DICDI Probable serine/threonine-protein ... | 96 | 0.023 | 38.9 | 32 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; ISS:dictyBase. | 598 | P18654 | 740 | KS6A3_MOUSE Ribosomal protein S6 kinase alpha... | 123 | 0.025 | 38.5 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0032496; P:response to lipopolysaccharide; IMP:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB. | 599 | P42683 | 508 | LCK_CHICK Proto-oncogene tyrosine-protein kin... | 81 | 0.025 | 38.5 | 27 | 46 | GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB. | 600 | P21802 | 821 | FGFR2_HUMAN Fibroblast growth factor receptor... | 98 | 0.025 | 38.5 | 31 | 42 | GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; ISS:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017134; F:fibroblast growth factor binding; IDA:UniProtKB.::GO:0005007; F:fibroblast growth factor-activated receptor activity; IDA:UniProtKB.::GO:0008201; F:heparin binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0030282; P:bone mineralization; ISS:UniProtKB.::GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0060667; P:branch elongation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; ISS:UniProtKB.::GO:0048755; P:branching morphogenesis of a nerve; ISS:UniProtKB.::GO:0060449; P:bud elongation involved in lung branching; ISS:UniProtKB.::GO:0045165; P:cell fate commitment; ISS:UniProtKB.::GO:0007267; P:cell-cell signaling; ISS:UniProtKB.::GO:0048557; P:embryonic digestive tract morphogenesis; ISS:UniProtKB.::GO:0009880; P:embryonic pattern specification; ISS:UniProtKB.::GO:0060664; P:epithelial cell proliferation involved in salivary gland morphogenesis; ISS:UniProtKB.::GO:0035603; P:fibroblast growth factor receptor signaling pathway involved in hemopoiesis; ISS:UniProtKB.::GO:0060595; P:fibroblast growth factor receptor signaling pathway involved in mammary gland specification; ISS:UniProtKB.::GO:0035602; P:fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow; ISS:UniProtKB.::GO:0035607; P:fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development; ISS:UniProtKB.::GO:0035604; P:fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow; ISS:UniProtKB.::GO:0031069; P:hair follicle morphogenesis; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0032808; P:lacrimal gland development; ISS:UniProtKB.::GO:0060601; P:lateral sprouting from an epithelium; ISS:UniProtKB.::GO:0060174; P:limb bud formation; ISS:UniProtKB.::GO:0048286; P:lung alveolus development; ISS:UniProtKB.::GO:0060463; P:lung lobe morphogenesis; ISS:UniProtKB.::GO:0060484; P:lung-associated mesenchyme development; ISS:UniProtKB.::GO:0060615; P:mammary gland bud formation; ISS:UniProtKB.::GO:0003149; P:membranous septum morphogenesis; ISS:UniProtKB.::GO:0060915; P:mesenchymal cell differentiation involved in lung development; ISS:UniProtKB.::GO:0060916; P:mesenchymal cell proliferation involved in lung development; ISS:UniProtKB.::GO:0030901; P:midbrain development; ISS:UniProtKB.::GO:0035264; P:multicellular organism growth; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0035265; P:organ growth; ISS:UniProtKB.::GO:0030916; P:otic vesicle formation; ISS:UniProtKB.::GO:0003148; P:outflow tract septum morphogenesis; ISS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051781; P:positive regulation of cell division; ISS:UniProtKB.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISS:UniProtKB.::GO:0010518; P:positive regulation of phospholipase activity; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0009791; P:post-embryonic development; ISS:UniProtKB.::GO:0060527; P:prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis; ISS:UniProtKB.::GO:0060523; P:prostate epithelial cord elongation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0021860; P:pyramidal neuron development; ISS:UniProtKB.::GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; ISS:UniProtKB.::GO:0010453; P:regulation of cell fate commitment; ISS:UniProtKB.::GO:0040036; P:regulation of fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; ISS:UniProtKB.::GO:0045667; P:regulation of osteoblast differentiation; TAS:UniProtKB.::GO:0033688; P:regulation of osteoblast proliferation; TAS:UniProtKB.::GO:0051150; P:regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0008589; P:regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0060529; P:squamous basal epithelial stem cell differentiation involved in prostate gland acinus development; ISS:UniProtKB.::GO:0001657; P:ureteric bud development; ISS:UniProtKB.::GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; ISS:UniProtKB.::GO:0021847; P:ventricular zone neuroblast division; ISS:UniProtKB. | 601 | Q91285 | 816 | FGFR1_PLEWA Fibroblast growth factor receptor... | 79 | 0.026 | 38.5 | 32 | 44 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0008284; P:positive regulation of cell proliferation; IEA:InterPro. |
