rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | B2GUS6 | 443 | KDM8_XENTR Lysine-specific demethylase 8 OS=X... | 325 | 0.000000000004 | 70.1 | 24 | 36 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | Q497B8 | 414 | KDM8_RAT Lysine-specific demethylase 8 OS=Rat... | 186 | 0.00000000002 | 68.2 | 26 | 38 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q9CXT6 | 414 | KDM8_MOUSE Lysine-specific demethylase 8 OS=M... | 186 | 0.00000000002 | 67.8 | 26 | 38 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | Q8N371 | 416 | KDM8_HUMAN Lysine-specific demethylase 8 OS=H... | 334 | 0.00000000009 | 66.2 | 24 | 36 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | B5XF11 | 404 | KDM8_SALSA Lysine-specific demethylase 8 OS=S... | 304 | 0.00000000009 | 66.2 | 24 | 37 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q1JP61 | 406 | KDM8_BOVIN Lysine-specific demethylase 8 OS=B... | 311 | 0.0000000001 | 65.9 | 23 | 35 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | A8E534 | 406 | KDM8_DANRE Lysine-specific demethylase 8 OS=D... | 74 | 0.000000003 | 61.6 | 46 | 55 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q55DF5 | 448 | JMJCD_DICDI JmjC domain-containing protein D ... | 189 | 0.000000005 | 60.8 | 28 | 40 | | | | | | | | | | | | | | | | | | | | | | 9 | Q54FG7 | 474 | JMJCF_DICDI JmjC domain-containing protein F ... | 108 | 0.0000001 | 56.6 | 33 | 48 | | | | | | | | | | | | | | | | | | | | | | 10 | Q54LV7 | 415 | JMJCC_DICDI JmjC domain-containing protein C ... | 195 | 0.000006 | 51.2 | 25 | 36 | | | | | | | | | | | | | | | | | | | | | | 11 | P0C872 | 316 | JMJD7_MOUSE JmjC domain-containing protein 7 ... | 336 | 0.000009 | 50.4 | 22 | 37 | | | | | | | | | | | | | | | | | | | | | | 12 | P0C870 | 316 | JMJD7_HUMAN JmjC domain-containing protein 7 ... | 336 | 0.00003 | 48.9 | 22 | 36 | | | | | | | | | | | | | | | | | | | | | | 13 | Q8BLR9 | 349 | HIF1N_MOUSE Hypoxia-inducible factor 1-alpha ... | 163 | 0.0001 | 46.6 | 23 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0071532; F:ankyrin repeat binding; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005112; F:Notch binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0036140; F:peptidyl-asparagine 3-dioxygenase activity; ISS:UniProtKB.::GO:0036139; F:peptidyl-histidine dioxygenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0045746; P:negative regulation of Notch signaling pathway; ISS:UniProtKB.::GO:0042265; P:peptidyl-asparagine hydroxylation; ISS:UniProtKB.::GO:0036138; P:peptidyl-histidine hydroxylation; ISS:UniProtKB.::GO:0045663; P:positive regulation of myoblast differentiation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q9NWT6 | 349 | HIF1N_HUMAN Hypoxia-inducible factor 1-alpha ... | 164 | 0.0003 | 45.8 | 23 | 35 | | | | | | | | | | | | | | | | | | | | | | 15 | P59723 | 344 | HIF1N_DANRE Hypoxia-inducible factor 1-alpha ... | 152 | 0.002 | 42.7 | 24 | 36 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0036140; F:peptidyl-asparagine 3-dioxygenase activity; ISS:UniProtKB.::GO:0036139; F:peptidyl-histidine dioxygenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042265; P:peptidyl-asparagine hydroxylation; ISS:UniProtKB.::GO:0036138; P:peptidyl-histidine hydroxylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q5UQY3 | 604 | YL887_MIMIV Putative JmjC domain-containing p... | 36 | 0.003 | 43.1 | 47 | 72 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 17 | Q6AXL5 | 449 | HBAP1_DANRE HSPB1-associated protein 1 homolo... | 155 | 0.082 | 38.1 | 24 | 36 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 18 | A5G320 | 327 | MDH_ACICJ Malate dehydrogenase OS=Acidiphiliu... | 192 | 0.12 | 37.4 | 26 | 36 | | | | | | | | | | | GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 19 | Q08BV2 | 326 | TYW5_DANRE tRNA wybutosine-synthesizing prote... | 136 | 0.21 | 37 | 21 | 37 | | | | | | | | | | | GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0000049; F:tRNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0031591; P:wybutosine biosynthetic process; ISS:UniProtKB. | 20 | Q54CS7 | 353 | JMJCE_DICDI JmjC domain-containing protein E ... | 75 | 0.39 | 35.8 | 29 | 48 | | | | | | | | | | | | | | | | | | | | | | 21 | Q4WVD1 | 1047 | LCMT2_ASPFU Leucine carboxyl methyltransferas... | 36 | 0.95 | 35 | 47 | 67 | | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 22 | A2RSX7 | 315 | TYW5_MOUSE tRNA wybutosine-synthesizing prote... | 34 | 1.3 | 34.3 | 35 | 59 | | | | | | | | | | | GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0000049; F:tRNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0031591; P:wybutosine biosynthetic process; ISS:UniProtKB. | 23 | A9IIS3 | 329 | MDH_BORPD Malate dehydrogenase OS=Bordetella ... | 90 | 1.4 | 34.3 | 32 | 42 | | | | | | | | | | | GO:0030060; F:L-malate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.::GO:0006108; P:malate metabolic process; IEA:InterPro.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW. | 24 | A2RUC4 | 315 | TYW5_HUMAN tRNA wybutosine-synthesizing prote... | 34 | 1.6 | 33.9 | 35 | 59 | | | | | | | | | | | GO:0005506; F:iron ion binding; IDA:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000049; F:tRNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0031591; P:wybutosine biosynthetic process; IDA:UniProtKB. | 25 | E1C7T6 | 318 | TYW5_CHICK tRNA wybutosine-synthesizing prote... | 34 | 1.9 | 33.9 | 35 | 59 | | | | | | | | | | | GO:0005506; F:iron ion binding; ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0000049; F:tRNA binding; ISS:UniProtKB. | | | | | | | | | | GO:0031591; P:wybutosine biosynthetic process; ISS:UniProtKB. | 26 | Q9VD28 | 408 | JMJD6_DROME Bifunctional arginine demethylase... | 39 | 1.9 | 33.9 | 33 | 51 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0070815; F:peptidyl-lysine 5-dioxygenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035212; P:cell competition in a multicellular organism; IMP:FlyBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:FlyBase.::GO:0046329; P:negative regulation of JNK cascade; IGI:FlyBase.::GO:0018395; P:peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 27 | Q623U2 | 397 | JMJD6_CAEBR Bifunctional arginine demethylase... | 32 | 2 | 33.9 | 38 | 63 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0070815; F:peptidyl-lysine 5-dioxygenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0018395; P:peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q67XX3 | 502 | FB252_ARATH F-box protein At5g06550 OS=Arabid... | 37 | 2.8 | 33.5 | 35 | 57 | | | | | | | | | | | | | | | | | | | | | | 29 | Q99MD6 | 697 | TRXR3_MOUSE Thioredoxin reductase 3 OS=Mus mu... | 155 | 3 | 33.5 | 25 | 39 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0050661; F:NADP binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006749; P:glutathione metabolic process; IDA:MGI.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 30 | Q6C3P4 | 989 | LCMT2_YARLI Leucine carboxyl methyltransferas... | 62 | 4.1 | 33.1 | 31 | 50 | | | | | | | | | | | GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 31 | O13977 | 464 | JMJ1_SCHPO JmjC domain-containing protein 1 O... | 27 | 4.8 | 32.7 | 33 | 63 | | | | | | | | | | | | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. |