rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9Y6F1 | 533 | PARP3_HUMAN Poly [ADP-ribose] polymerase 3 OS... | 159 | 0.000001 | 54.7 | 30 | 45 | GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0006471; P:protein ADP-ribosylation; TAS:ProtInc. | 2 | Q9UKK3 | 1724 | PARP4_HUMAN Poly [ADP-ribose] polymerase 4 OS... | 102 | 0.0004 | 46.6 | 29 | 45 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; NAS:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019899; F:enzyme binding; IDA:MGI.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IMP:UniProtKB.::GO:0006281; P:DNA repair; NAS:UniProtKB.::GO:0006954; P:inflammatory response; IMP:UniProtKB.::GO:0006471; P:protein ADP-ribosylation; NAS:UniProtKB.::GO:0042493; P:response to drug; NAS:UniProtKB.::GO:0006810; P:transport; NAS:UniProtKB. | 3 | O95271 | 1327 | TNKS1_HUMAN Tankyrase-1 OS=Homo sapiens (Huma... | 233 | 0.006 | 43.1 | 21 | 38 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; TAS:BHF-UCL.::GO:0005643; C:nuclear pore; TAS:BHF-UCL.::GO:0000242; C:pericentriolar material; TAS:BHF-UCL. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL. | | | | | | | | | | GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0070212; P:protein poly-ADP-ribosylation; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; TAS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 4 | Q6PFX9 | 1320 | TNKS1_MOUSE Tankyrase-1 OS=Mus musculus (Mous... | 233 | 0.007 | 42.7 | 21 | 38 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 5 | Q7EYV7 | 977 | PARP1_ORYSJ Poly [ADP-ribose] polymerase 1 OS... | 126 | 0.5 | 36.6 | 26 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IEA:InterPro. | 6 | Q9ZP54 | 983 | PARP1_ARATH Poly [ADP-ribose] polymerase 1 OS... | 116 | 0.78 | 36.2 | 28 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEP:TAIR.::GO:0006471; P:protein ADP-ribosylation; IDA:TAIR.::GO:0009628; P:response to abiotic stimulus; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IEP:TAIR.::GO:0006979; P:response to oxidative stress; IEP:TAIR. | 7 | Q9ZSV1 | 980 | PARP1_MAIZE Poly [ADP-ribose] polymerase 1 OS... | 115 | 0.8 | 35.8 | 25 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IEA:InterPro. | 8 | P51531 | 1590 | SMCA2_HUMAN Probable global transcription act... | 52 | 0.88 | 35.8 | 33 | 48 | GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0016514; C:SWI/SNF complex; IDA:UniProtKB.::GO:0071778; C:WINAC complex; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; TAS:BHF-UCL.::GO:0004386; F:helicase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 9 | Q7Z3E1 | 657 | PARPT_HUMAN TCDD-inducible poly [ADP-ribose] ... | 166 | 1.3 | 35 | 26 | 44 | | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 10 | P27008 | 1014 | PARP1_RAT Poly [ADP-ribose] polymerase 1 OS=R... | 176 | 1.4 | 35 | 22 | 38 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042769; P:DNA damage response, detection of DNA damage; IDA:RGD.::GO:0016540; P:protein autoprocessing; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 11 | Q8C1B2 | 657 | PARPT_MOUSE TCDD-inducible poly [ADP-ribose] ... | 168 | 1.6 | 35 | 24 | 42 | | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IMP:MGI.::GO:0008210; P:estrogen metabolic process; IMP:MGI.::GO:0060325; P:face morphogenesis; IMP:MGI.::GO:0008585; P:female gonad development; IMP:MGI.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0044236; P:multicellular organismal metabolic process; IMP:MGI.::GO:0006807; P:nitrogen compound metabolic process; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0006471; P:protein ADP-ribosylation; IDA:MGI.::GO:0048705; P:skeletal system morphogenesis; IMP:MGI.::GO:0048745; P:smooth muscle tissue development; IMP:MGI.::GO:0001570; P:vasculogenesis; IMP:MGI. | 12 | P11103 | 1013 | PARP1_MOUSE Poly [ADP-ribose] polymerase 1 OS... | 176 | 2.6 | 34.3 | 22 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006471; P:protein ADP-ribosylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 13 | Q9R152 | 1013 | PARP1_CRIGR Poly [ADP-ribose] polymerase 1 OS... | 176 | 2.7 | 34.3 | 22 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006471; P:protein ADP-ribosylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q0JMY1 | 605 | PRP2B_ORYSJ Poly [ADP-ribose] polymerase 2-B ... | 172 | 3 | 33.9 | 24 | 38 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IEA:InterPro. | 15 | Q9H2K2 | 1166 | TNKS2_HUMAN Tankyrase-2 OS=Homo sapiens (Huma... | 238 | 4.4 | 33.5 | 19 | 37 | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IC:BHF-UCL.::GO:0005635; C:nuclear envelope; IDA:BHF-UCL.::GO:0000242; C:pericentriolar material; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB. | | | | | | | | | | GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 16 | Q3UES3 | 1166 | TNKS2_MOUSE Tankyrase-2 OS=Mus musculus (Mous... | 106 | 5.1 | 33.5 | 27 | 39 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 17 | P31669 | 998 | PARP1_XENLA Poly [ADP-ribose] polymerase 1 OS... | 59 | 6.3 | 33.1 | 37 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006471; P:protein ADP-ribosylation; IEA:InterPro. | 18 | P09874 | 1014 | PARP1_HUMAN Poly [ADP-ribose] polymerase 1 OS... | 59 | 6.8 | 33.1 | 34 | 53 | GO:0005635; C:nuclear envelope; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IDA:BHF-UCL. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0070212; P:protein poly-ADP-ribosylation; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. |