| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q54E35 | 570 | GACEE_DICDI Rho GTPase-activating protein gac... | 119 | 0.001 | 42.4 | 24 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 2 | P70611 | 403 | DOC2A_RAT Double C2-like domain-containing pr... | 59 | 0.019 | 38.5 | 39 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016079; P:synaptic vesicle exocytosis; IEP:RGD. | 3 | Q14183 | 400 | DOC2A_HUMAN Double C2-like domain-containing ... | 59 | 0.021 | 38.1 | 39 | 59 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB. | 4 | Q8IYJ3 | 562 | SYTL1_HUMAN Synaptotagmin-like protein 1 OS=H... | 114 | 0.023 | 38.1 | 29 | 47 | GO:0019897; C:extrinsic to plasma membrane; ISS:UniProtKB.::GO:0042470; C:melanosome; ISS:UniProtKB.::GO:0005625; C:soluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 5 | Q7TNF0 | 405 | DOC2A_MOUSE Double C2-like domain-containing ... | 58 | 0.024 | 38.1 | 40 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:UniProtKB. | 6 | Q6DN14 | 999 | MCTP1_HUMAN Multiple C2 and transmembrane dom... | 107 | 0.025 | 38.1 | 25 | 50 | GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:HGNC. | | | | | | | | | | GO:0019722; P:calcium-mediated signaling; NAS:HGNC. | 7 | Q14184 | 412 | DOC2B_HUMAN Double C2-like domain-containing ... | 71 | 0.041 | 37.4 | 35 | 52 | GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; ISS:UniProtKB.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB. | 8 | P70169 | 412 | DOC2B_MOUSE Double C2-like domain-containing ... | 71 | 0.061 | 37 | 35 | 51 | GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0019905; F:syntaxin binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IMP:UniProtKB.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; ISS:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; ISS:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB. | 9 | Q9FVJ3 | 337 | AGD12_ARATH ADP-ribosylation factor GTPase-ac... | 84 | 0.061 | 36.6 | 27 | 48 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0005543; F:phospholipid binding; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; TAS:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 10 | P70610 | 412 | DOC2B_RAT Double C2-like domain-containing pr... | 72 | 0.068 | 36.6 | 35 | 51 | GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IDA:UniProtKB.::GO:0006887; P:exocytosis; IEP:RGD.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; IDA:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB. | 11 | P24505 | 427 | SY61_DISOM Synaptotagmin-A OS=Discopyge ommat... | 109 | 0.07 | 36.6 | 29 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 12 | Q99N80 | 567 | SYTL1_MOUSE Synaptotagmin-like protein 1 OS=M... | 67 | 0.11 | 36.2 | 31 | 54 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0042470; C:melanosome; IDA:UniProtKB.::GO:0005625; C:soluble fraction; IDA:UniProtKB. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; IDA:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IDA:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 13 | P47709 | 684 | RP3A_RAT Rabphilin-3A OS=Rattus norvegicus (R... | 70 | 0.14 | 35.8 | 34 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:RGD.::GO:0019898; C:extrinsic to membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008430; F:selenium binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 14 | P47708 | 681 | RP3A_MOUSE Rabphilin-3A OS=Mus musculus (Mous... | 70 | 0.15 | 35.8 | 34 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 15 | Q9Y2J0 | 694 | RP3A_HUMAN Rabphilin-3A OS=Homo sapiens (Huma... | 70 | 0.17 | 35.4 | 34 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 16 | Q8VHQ7 | 672 | SYTL4_RAT Synaptotagmin-like protein 4 OS=Rat... | 110 | 0.85 | 33.5 | 27 | 45 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0019898; C:extrinsic to membrane; ISS:UniProtKB.::GO:0030667; C:secretory granule membrane; IDA:RGD.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 17 | Q06846 | 704 | RP3A_BOVIN Rabphilin-3A OS=Bos taurus (Bovine... | 70 | 0.26 | 35 | 34 | 53 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 18 | Q9R0N5 | 386 | SYT5_MOUSE Synaptotagmin-5 OS=Mus musculus (M... | 109 | 0.27 | 35 | 26 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 19 | P47861 | 386 | SYT5_RAT Synaptotagmin-5 OS=Rattus norvegicus... | 109 | 0.28 | 34.7 | 26 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017156; P:calcium ion-dependent exocytosis; NAS:RGD. | 20 | Q96C24 | 671 | SYTL4_HUMAN Synaptotagmin-like protein 4 OS=H... | 66 | 1 | 33.5 | 27 | 52 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0019898; C:extrinsic to membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0050714; P:positive regulation of protein secretion; IMP:UniProtKB. | 21 | Q9R0N9 | 491 | SYT9_MOUSE Synaptotagmin-9 OS=Mus musculus (M... | 63 | 0.35 | 34.7 | 35 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 22 | Q925C0 | 491 | SYT9_RAT Synaptotagmin-9 OS=Rattus norvegicus... | 63 | 0.38 | 34.7 | 35 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031045; C:dense core granule; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030667; C:secretory granule membrane; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0017158; P:regulation of calcium ion-dependent exocytosis; IMP:RGD.::GO:0050796; P:regulation of insulin secretion; IMP:RGD. | 23 | Q8L7A4 | 385 | AGD11_ARATH Probable ADP-ribosylation factor ... | 68 | 0.49 | 34.3 | 28 | 54 | | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. | 24 | Q812E4 | 753 | SYTL5_RAT Synaptotagmin-like protein 5 OS=Rat... | 57 | 0.52 | 34.3 | 32 | 53 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 25 | Q80T23 | 753 | SYTL5_MOUSE Synaptotagmin-like protein 5 OS=M... | 57 | 0.57 | 34.3 | 33 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IDA:MGI.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 26 | P41885 | 1106 | RBF1_CAEEL Rabphilin-1 OS=Caenorhabditis eleg... | 92 | 0.8 | 33.5 | 23 | 42 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IDA:WormBase. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase. | 27 | O00445 | 386 | SYT5_HUMAN Synaptotagmin-5 OS=Homo sapiens (H... | 110 | 0.88 | 33.5 | 26 | 45 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:ProtInc. | 28 | Q9R0Q1 | 673 | SYTL4_MOUSE Synaptotagmin-like protein 4 OS=M... | 57 | 1.5 | 32.7 | 35 | 51 | GO:0019898; C:extrinsic to membrane; IDA:UniProtKB.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042043; F:neurexin family protein binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IDA:MGI.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB. | | | | | | | | | | GO:0006887; P:exocytosis; IDA:MGI.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI. | 29 | Q93XX4 | 751 | C2D61_ARATH C2 domain-containing protein At1g... | 60 | 1.5 | 32.7 | 33 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | | 30 | Q9ESN1 | 387 | DOC2G_MOUSE Double C2-like domain-containing ... | 72 | 1.6 | 32.7 | 32 | 47 | GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro. | | | | | | | | | | GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 31 | Q5T7P8 | 510 | SYT6_HUMAN Synaptotagmin-6 OS=Homo sapiens (H... | 55 | 2.6 | 32 | 45 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0097038; C:perinuclear endoplasmic reticulum; ISS:BHF-UCL.::GO:0000300; C:peripheral to membrane of membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | GO:0060478; P:acrosomal vesicle exocytosis; IMP:BHF-UCL. |
