| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | O60285 | 661 | NUAK1_HUMAN NUAK family SNF1-like kinase 1 OS... | 260 | 0.19 | 39.7 | 21 | 38 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030155; P:regulation of cell adhesion; IDA:UniProtKB.::GO:0042127; P:regulation of cell proliferation; TAS:UniProtKB.::GO:2000772; P:regulation of cellular senescence; IDA:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; IDA:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW. | 152 | P51954 | 1203 | NEK1_MOUSE Serine/threonine-protein kinase Ne... | 168 | 0.19 | 39.7 | 23 | 42 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IMP:MGI.::GO:0010212; P:response to ionizing radiation; IMP:MGI. | 153 | P34885 | 707 | KPC1B_CAEEL Protein kinase C-like 1B OS=Caeno... | 174 | 0.19 | 39.7 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 154 | Q61161 | 821 | M4K2_MOUSE Mitogen-activated protein kinase k... | 168 | 0.2 | 39.7 | 23 | 41 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006903; P:vesicle targeting; IDA:UniProtKB. | 155 | O94804 | 968 | STK10_HUMAN Serine/threonine-protein kinase 1... | 169 | 0.2 | 39.7 | 22 | 40 | GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042801; F:polo kinase kinase activity; TAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071593; P:lymphocyte aggregation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000401; P:regulation of lymphocyte migration; IMP:UniProtKB. | 156 | Q7KRY6 | 599 | NHK1_DROME Nucleosomal histone kinase 1 OS=Dr... | 168 | 0.21 | 39.3 | 21 | 41 | GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035184; F:histone threonine kinase activity; IDA:FlyBase. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007143; P:female meiosis; IMP:UniProtKB.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; IMP:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB. | 157 | Q80UW5 | 1551 | MRCKG_MOUSE Serine/threonine-protein kinase M... | 79 | 0.22 | 39.7 | 28 | 52 | GO:0031252; C:cell leading edge; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 158 | P50118 | 345 | MOS_PIG Proto-oncogene serine/threonine-prote... | 267 | 0.22 | 38.9 | 21 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 159 | Q9USX7 | 526 | PPK22_SCHPO Serine/threonine-protein kinase p... | 117 | 0.23 | 39.3 | 26 | 46 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0019236; P:response to pheromone; ISS:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 160 | P28708 | 518 | PRR1_YEAST Serine/threonine-protein kinase PR... | 67 | 0.23 | 39.3 | 31 | 49 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004702; F:receptor signaling protein serine/threonine kinase activity; IMP:SGD. | | | | | | | | | | GO:0031138; P:negative regulation of conjugation with cellular fusion; IMP:SGD.::GO:0046020; P:negative regulation of transcription from RNA polymerase II promoter by pheromones; IMP:SGD. | 161 | Q7YQL3 | 559 | PAK3_PONPY Serine/threonine-protein kinase PA... | 165 | 0.24 | 39.3 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 162 | Q7YQL4 | 559 | PAK3_PANTR Serine/threonine-protein kinase PA... | 165 | 0.24 | 39.3 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 163 | O75914 | 559 | PAK3_HUMAN Serine/threonine-protein kinase PA... | 165 | 0.24 | 39.3 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0060997; P:dendritic spine morphogenesis; TAS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; IDA:UniProtKB.::GO:0050808; P:synapse organization; TAS:UniProtKB. | 164 | Q5Q0U5 | 431 | SGK1_FUNHE Serine/threonine-protein kinase Sg... | 256 | 0.24 | 38.9 | 22 | 38 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 165 | Q62829 | 544 | PAK3_RAT Serine/threonine-protein kinase PAK ... | 165 | 0.24 | 39.3 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051020; F:GTPase binding; IDA:RGD.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; ISS:UniProtKB.::GO:0016358; P:dendrite development; ISS:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 166 | Q04899 | 451 | CDK18_MOUSE Cyclin-dependent kinase 18 OS=Mus... | 284 | 0.25 | 38.9 | 25 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 167 | O75716 | 305 | STK16_HUMAN Serine/threonine-protein kinase 1... | 280 | 0.25 | 38.5 | 23 | 36 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 168 | Q9Z2A0 | 559 | PDPK1_MOUSE 3-phosphoinositide-dependent prot... | 169 | 0.25 | 38.9 | 24 | 38 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003323; P:type B pancreatic cell development; IMP:UniProtKB. | 169 | B1WAS2 | 697 | HUNK_XENTR Hormonally up-regulated neu tumor-... | 155 | 0.26 | 39.3 | 23 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 170 | Q9P6P3 | 534 | PPK15_SCHPO Serine/threonine-protein kinase p... | 177 | 0.26 | 38.9 | 21 | 40 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-KW.::GO:0005816; C:spindle pole body; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase. | 171 | Q5ZJH6 | 468 | ULK3_CHICK Serine/threonine-protein kinase UL... | 269 | 0.26 | 38.9 | 22 | 38 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 172 | O64682 | 438 | PID_ARATH Protein kinase PINOID OS=Arabidopsi... | 210 | 0.27 | 38.9 | 25 | 40 | GO:0009986; C:cell surface; IDA:TAIR.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR. | | | | | | | | | | GO:0009734; P:auxin mediated signaling pathway; IMP:TAIR.::GO:0009926; P:auxin polar transport; IMP:TAIR.::GO:0048825; P:cotyledon development; IGI:UniProtKB.::GO:0009958; P:positive gravitropism; IMP:TAIR.::GO:0080167; P:response to karrikin; IEP:TAIR.::GO:0048767; P:root hair elongation; IMP:TAIR.::GO:0048766; P:root hair initiation; IMP:TAIR. | 173 | P09215 | 673 | KPCD_RAT Protein kinase C delta type OS=Rattu... | 253 | 0.27 | 38.9 | 22 | 38 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0070976; F:TIR domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0015810; P:aspartate transport; IMP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0032963; P:collagen metabolic process; IMP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 174 | Q61036 | 559 | PAK3_MOUSE Serine/threonine-protein kinase PA... | 165 | 0.27 | 38.9 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:UniProtKB.::GO:0016358; P:dendrite development; IMP:UniProtKB.::GO:0030833; P:regulation of actin filament polymerization; ISS:UniProtKB. | 175 | Q9WTQ0 | 707 | KPCT_RAT Protein kinase C theta type OS=Rattu... | 260 | 0.28 | 38.9 | 20 | 38 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031594; C:neuromuscular junction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0051491; P:positive regulation of filopodium assembly; IMP:RGD.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:RGD.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0019229; P:regulation of vasoconstriction; IEP:RGD.::GO:0045730; P:respiratory burst; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD. | 176 | Q12851 | 820 | M4K2_HUMAN Mitogen-activated protein kinase k... | 168 | 0.31 | 38.9 | 23 | 41 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; TAS:ProtInc.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; IDA:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0046330; P:positive regulation of JNK cascade; IDA:UniProtKB.::GO:0006903; P:vesicle targeting; NAS:UniProtKB. | 177 | P70218 | 827 | M4K1_MOUSE Mitogen-activated protein kinase k... | 167 | 0.31 | 38.9 | 22 | 38 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IDA:UniProtKB. | 178 | Q02111 | 707 | KPCT_MOUSE Protein kinase C theta type OS=Mus... | 260 | 0.31 | 38.9 | 20 | 38 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001772; C:immunological synapse; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:MGI. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0032740; P:positive regulation of interleukin-17 production; IMP:UniProtKB.::GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:2000318; P:positive regulation of T-helper 17 type immune response; IMP:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB. | 179 | P0C5K0 | 362 | SG110_MOUSE Putative uncharacterized serine/t... | 120 | 0.32 | 38.5 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 180 | P92199 | 1173 | ROCK_CAEEL Rho-associated protein kinase let-... | 78 | 0.32 | 38.9 | 24 | 53 | GO:0005913; C:cell-cell adherens junction; IDA:WormBase.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0043292; C:contractile fiber; IDA:WormBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0010172; P:embryonic body morphogenesis; IMP:WormBase.::GO:0001703; P:gastrulation with mouth forming first; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; TAS:WormBase. | 181 | O55173 | 559 | PDPK1_RAT 3-phosphoinositide-dependent protei... | 169 | 0.33 | 38.5 | 24 | 38 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
